Lecture Notes: TRT and Hormone Optimization

Introduction

• Discussion of trying Human Chorionic Gonadotropin (HCG) for better orgasm intensity.
• Current usage: Testosterone Replacement Therapy (TRT) with cream.
• Dosage question: 250 every other day.

Key Points

HCG Usage

• Purpose: Considered to potentially restore previous levels of intensity/volume rather than enhancing beyond past levels.
• Dosage:
  • Twice a week on HCG is often sufficient.
  • Dosage range suggested: 350-500 IUs, depending on tolerance.
• Effects: Can help with volume restoration.
  • Not a fast-acting, short-lasting effect; effects can last beyond immediate dosage.

Potential Issues

• DHT Levels:
  • Too much DHT can lower SHBG and E2.
  • Cream vs. injections: cream may show different DHT levels due to local tissue production.
  • Higher free testosterone often observed with cream due to thinnest absorption layer in scrotum.
• Patient Experience: Patient anecdote - injections showed higher DHT than creams despite lower total testosterone.

Practical Considerations

• Patient Guidance:
  • Open, facilitative approach to patient preferences if safety is ensured.
  • Trial and error approach suggested to determine personal response.
• Injection Considerations:
  • Avoid using large gauge needles (e.g., 18 gauge).

Hormone Mechanics

• DHT and Testosterone:
  • Serum DHT levels may not be reflective of actual physiological status due to local tissue production.
  • The cream provides a high free testosterone level due to frequent administration.

Conclusion

• Experimenting with HCG in small doses is generally safe.
• For further learning, viewers are encouraged to continue exploring TRT and hormone optimization resources.