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Week 6 lecture 5

Oct 10, 2024

Lecture Notes on Bone Structure

1. Introduction to Bone Structure

  • Compact Bone
    • Found on the outer surface of all bones.
    • Not solid; mostly spongy bone inside.
    • Composed of compact and spongy bone in varying proportions.
  • Spongy Bone
    • Found within bones, surrounded by compact bone.
    • Contains trabeculae and bone marrow.

2. Compact Bone Details

  • Osteons
    • Found only in the diaphysis of long bones.
    • Made of concentric lamellae around a central Haversion Canal.
    • Provide structural strength, allowing for movement without bone breakage.
  • Functions of Compact Bone (Cortical Bone)
    • Protection: Protects soft tissues like brain, heart, and bone marrow.
    • Anchoring Site: Provides attachment for tendons (muscle to bone) and ligaments (bone to bone).
    • Locomotion: Particularly in long bones, involved in movement.

3. Circumferential Lamellae

  • Found on the outermost surface of the bone.
  • Consist of rings (lamellae) that provide an attachment site for connective tissue.

4. Osteon Structure

  • Long cylindrical structures with a central Haversion Canal.
  • Haversion Canal
    • Contains blood vessels, lymph vessels, and neurons.
    • Crucial for nutrition and waste removal of bone cells.
  • Collagen Fibers
    • Laid in opposing angles to handle torsion, preventing bone breakage during movement.

5. Spongy Bone Features

  • Functions
    • Provides internal support through trabeculae.
    • Houses stem cells due to blood-rich endosteum.
    • Considered bioavailable for minerals like calcium.
  • Structure
    • Trabeculae provide support and contain bone marrow.
    • Osteocytes reside in lacunae, not organized in concentric lamellae.

6. Differences Between Compact and Spongy Bone

  • Compact Bone
    • Dense, highly organized in osteons with concentric lamellae.
    • Primarily for structural integrity and support.
  • Spongy Bone
    • Less dense, contains trabeculae, and is more physiologically active.
    • Provides support, mineral storage, and houses marrow.
    • Contains blood vessels on the surface, not within.

7. Trabeculae Details

  • Internal Structure
    • Contains osteocytes but lacks blood vessels.
  • External Features
    • Highly vascularized surface with osteoblasts and osteoclasts.
    • Endosteum present, composed of blood vessels and stem cells.

8. Importance of Collagen and Osteons

  • Collagen fibers in osteons are key for handling torsion.
  • Osteons prevent snapping in long bones during movement.

9. Marrow Characteristics

  • Red Marrow
    • Contains actively reproducing hematopoietic stem cells.
    • Found in spongy bone.
  • Yellow Marrow
    • Fatty tissue, more prevalent in long bones during adulthood.

10. Additional Notes

  • Volkmann's Canals
    • Connect exterior bone surface to interior osteons.
    • Facilitate nutrient and blood supply to bone.
  • Bone's Vascularity
    • Highly vascularized with networks of blood vessels for nutrient delivery.

11. Conclusion

  • Understanding the detailed structure and function of bone components (compact and spongy) is essential for appreciating the complexity and functionality of the skeletal system.