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Blood Vessel Structure & Function

Jul 3, 2025

Overview

This lecture explains the structure and function of blood vessels in the circulatory system, detailing how blood flows from the heart throughout the body and back.

Blood Vessel Structure & Functions

  • The circulatory system is a closed network that starts and ends at the heart.
  • Blood vessels are dynamic organs that contract and expand to regulate blood flow and pressure.
  • There are three main types of blood vessels: arteries, veins, and capillaries.
  • Arterioles are small branches of arteries leading to capillaries; venules gather blood from capillaries to veins.
  • Blood vessels are structured in three layers: tunica intima (inner), tunica media (middle), and tunica externa (outer).

Layers of Blood Vessels (Tunics)

  • Tunica intima: innermost layer, contains endothelium for smooth blood flow.
  • Tunica media: middle layer of smooth muscle and elastin, controls vasoconstriction and vasodilation.
  • Tunica externa: outer layer made of collagen fibers, provides protection and support.

Types of Arteries and Their Roles

  • Elastic arteries (like the aorta) absorb pressure from heartbeats using more elastin.
  • Muscular arteries (like brachial and radial) distribute blood to body parts and have a thick tunica media for regulation.
  • Arterioles control blood flow to capillaries and help regulate blood pressure.

Capillaries and Exchange

  • Capillaries have thin walls (one epithelial cell layer) for easy exchange of oxygen, nutrients, and wastes.
  • Capillary beds regulate blood pressure and temperature via sphincters that control blood flow.

Veins and Blood Return

  • Venules collect blood from capillaries and merge into veins that return to the heart.
  • Veins have low pressure and use valves (especially in limbs) to prevent backflow.

Blood Flow Pathway Example

  • Blood leaves the left ventricle via the aorta, travels through arteries and arterioles to capillaries, then returns via venules and veins.
  • The full circuit from the heart to the thumb and back takes about one minute.

Key Terms & Definitions

  • Artery — Blood vessel that carries blood away from the heart.
  • Vein — Blood vessel that returns blood back to the heart.
  • Capillary — Smallest blood vessel where exchange of materials occurs.
  • Arteriole — Small artery leading to a capillary.
  • Venule — Small vein collecting blood from capillaries.
  • Tunica intima — Innermost blood vessel layer with endothelium.
  • Tunica media — Middle, muscular, and elastic vessel layer.
  • Tunica externa — Outer protective vessel layer of collagen.
  • Vasoconstriction — Narrowing of blood vessels.
  • Vasodilation — Widening of blood vessels.
  • Endothelium — Smooth inner lining of blood vessels.

Action Items / Next Steps

  • Review the blood flow pathway and structure of vessel layers.
  • Study the role of vasoconstriction and vasodilation in regulating blood pressure.