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Comprehensive Overview of ADHD

May 13, 2025

Lecture Notes: Understanding ADHD

Introduction

  • ADHD (Attention Deficit Hyperactivity Disorder):
    • Neurodevelopmental disorder beginning in childhood.
    • Involves symptoms in two domains: inattention and hyperactivity.
    • Often noticed due to poor school performance or disruptive behavior.
  • Controversy:
    • Risks of both underdiagnosis and overdiagnosis.
      • Underdiagnosis: Can lead to severe life impairments (low academic performance, unstable relationships).
      • Overdiagnosis: May stigmatize children, foster dependence on medication, or overlook environmental issues.

Core Symptom Domains

Inattention

  • Difficulties in maintaining focus.
  • Symptoms: Captured in the mnemonic "DETAILS OFF".
    • Disorganized, Easily distracted, Task avoidance, Appears to ignore instructions, Incomplete tasks, Loses things, Sloppy work.
  • People with ADHD might focus well on subjects of interest.

Hyperactivity

  • High energy levels leading to impulsivity.
  • Symptoms: Captured in the mnemonic "HE RILED UP".
    • Hyperactive, Energetic, Runs around, Interrupts or intrudes, Loud, Effusive, Difficulty waiting, Unseated, Premature answers.

Diagnosis Challenges and Mnemonics

  • ADHD does not require both inattention and hyperactivity.
  • FIDGETY Mnemonic:
    • Functionally impairing impulsivity/distractibility.
    • Inattention greater than expected.
    • Diagnosed by exclusion, Evidence across settings.
    • Timing of onset before age 12.
    • Young age onset.
  • Diagnosis of exclusion: Other causes must be ruled out.

Incidence and Demographics

  • Affects ~10% of children, 5% of adults.
  • Most common is inattentive subtype.
  • High heritability (~75%), environmental factors also play a role.
  • Onset typically between ages 3-8, more common in males (2:1 ratio).
  • Chronic and enduring symptoms.

Impacts and Treatment

Impacts

  • Educational, relational, and psychiatric challenges in children.
  • In adults: linked to academic, job, and personal challenges.

Treatments

  • Behavioral Therapy:
    • Includes CBT and family therapy.
    • Medium effect size (0.6 - 0.7).
  • Medications:
    • Stimulants: Methylphenidate (Ritalin) and Amphetamine salts (Adderall).
      • High effect size (> 1.0), but risks include growth restriction, appetite suppression, insomnia.
    • Non-stimulants: Atomoxetine, Guanfacine, Clonidine.
      • Lower effect size (~0.5), used when stimulants are unsuitable.

Summary

  • ADHD requires careful screening and diagnosis.
  • Effective treatments can lead to significant improvements in functioning.
  • Important to consider potential downsides of diagnosis and rule out other factors.

Conclusion

  • Gratifying to work with individuals with ADHD due to potential for dramatic improvements.
  • Further reading: "Memorable Psychiatry" book recommended.

These notes summarize key points on ADHD, diagnosis challenges, impacts, and treatment options.