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Cell Osmosis and Tonicity

Sep 4, 2025

Overview

This lecture explains osmosis, tonicity, and their effects on cells, including demonstrations using dialysis tubing to illustrate hypotonic, hypertonic, and isotonic solutions.

Osmosis and Semi-Permeable Membranes

  • Osmosis is the movement of water molecules across a semi-permeable membrane from higher to lower water concentration.
  • Semi-permeable membranes, like those in red blood cells, allow water movement but restrict certain solutes.

Tonicity and Its Classifications

  • Tonicity measures the osmotic pressure between two solutions separated by a semi-permeable membrane.
  • Tonicity is determined by solutes that cannot pass through the membrane, such as sugar.
  • There are three types of tonicity: hypotonic, hypertonic, and isotonic.

Hypotonic Solutions

  • In hypotonic solutions, solute concentration is higher inside the cell than outside, causing water to enter the cell.
  • Excess water entry can cause the cell to swell and possibly rupture (lysis).
  • Demonstration: Dialysis tubing filled with sugar solution gains weight after being placed in water due to water influx.

Hypertonic Solutions

  • In hypertonic solutions, solute concentration is higher outside the cell, causing water to leave the cell.
  • Water loss results in cell shrinkage, known as crenation.
  • Demonstration: Dialysis tubing filled with water loses weight after being placed in concentrated sugar solution due to water loss.

Isotonic Solutions

  • In isotonic solutions, solute concentrations inside and outside the cell are equal.
  • Water moves in and out at equal rates, so cell size remains stable.
  • Demonstration: Dialysis tubing filled with water shows no weight change when placed in water.

Key Terms & Definitions

  • Osmosis — Movement of water across a semi-permeable membrane from high to low concentration.
  • Semi-permeable membrane — A barrier that allows certain molecules (like water) to pass but blocks others.
  • Tonicity — The measure of osmotic pressure between two solutions, influenced by non-permeable solutes.
  • Hypotonic — Solution with lower solute concentration outside the cell, leading to water entering the cell.
  • Hypertonic — Solution with higher solute concentration outside the cell, leading to water leaving the cell.
  • Isotonic — Solution with equal solute concentration inside and outside the cell.
  • Crenate — The shrinking of a cell due to water loss.
  • Lysis — The rupture or bursting of a cell due to excess water intake.

Action Items / Next Steps

  • Review key definitions and effects of each tonicity type on cells.
  • Prepare for possible lab activity demonstrating osmosis and tonicity using dialysis tubing.