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Key Points on Oral Pathology Topics

Apr 27, 2025

Oral Pathology Lecture Notes

Introduction

  • Presenter: Ryan
  • Topic: Oral Pathology
  • Focus on high-yield content for exams like NBDA Part 2, ASE, and board exams
  • Organized by tissue type and lesion type (reactive, infectious, immunologic, etc.)
  • Content adapted from "Mosby's Review for the NBDA Part 2"

Developmental Conditions

Cleft Lip and Cleft Palate

  • Cleft Lip:
    • Incidence: 1 in 1,000 births
    • More common unilaterally (80%) vs. bilaterally (20%)
    • Caused by lack of fusion between medial nasal process and maxillary process
  • Cleft Palate:
    • Incidence: 1 in 2,000 births
    • Caused by lack of fusion between palatal shelves
    • Can lead to unilateral or bilateral clefts

Lip Pits

  • Imagination at corners of the mouth or near the midline
  • Van der Woude Syndrome: Includes cleft lip/palate and lip pits

Fordyce Granules

  • Ectopic sebaceous glands
  • Benign; no treatment necessary
  • Located on buccal or labial mucosa

Leukoedema

  • Whitish-grey edematous lesion on buccal mucosa
  • Lesion dissipates when cheek is stretched

Lingual Thyroid and Thyroglossal Duct Cysts

  • Lingual thyroid: Thyroid tissue mass at midline base of tongue
  • Thyroglossal duct cyst: Midline neck swelling
  • Both occur along the embryonic path of thyroid descent

Geographic Tongue

  • Also known as benign migratory glossitis or erythema migrans
  • White annular lesions with red islands; lesions migrate over time
  • Occasionally painful; no definitive treatment

Fissured Tongue

  • Characterized by folds and furrows on tongue dorsum
  • Part of Melkersson-Rosenthal syndrome which includes:
    • Fissured tongue
    • Granulomatous cheilitis (lip inflammation)
    • Facial paralysis (Bell's palsy)

Angiomas

General Information

  • Angiomas are tumors composed of blood or lymph vessels

Types of Angiomas

  • Cherry Angioma: Common, benign red mole
  • Hemangioma: Congenital capillary proliferation; often involutes with age
  • Lymphangioma: Rare, purple spots on tongue; cystic hygroma if in neck

Sturge-Weber Syndrome

  • Involves angiomas of leptomeninges (arachnoid and pia mater) and skin

Bone Growths and Cysts

Exostosis and Torus

  • Excessive cortical bone growth
  • Buccal exostosis and palatal torus based on location

Dermoid Cyst

  • Midline mass with doughy consistency; can be intraoral or extraoral

Branchial Cyst

  • Lateral neck swelling; epithelial cyst in lymph node

Oral Lymphoepithelial Cyst

  • Equivalent of branchial cyst in oral mucosa

Stafne Bone Defect

  • Radiolucency in posterior mandible; variation of normal anatomy

Nasopalatine Duct Cyst

  • Heart-shaped radiolucency in nasopalatine canal

Globulomaxillary Lesion

  • Radiolucency between maxillary canine and lateral incisor

Traumatic Bone Cyst

  • Large radiolucency scalloped around roots (pseudocyst)
  • Typically found in teenage mandibles; associated with trauma

Conclusion

  • End of lecture on developmental conditions
  • Encouragement to like, subscribe for more content