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Chemical Foundations of Life

Sep 21, 2025

Overview

This lecture outlines the chemical basis of life, covering the nature of elements and atoms, types of chemical bonds, molecular structure, and the basics of chemical reactions essential to biology.

The Chemical Context of Life

  • Living organisms are governed by the laws of physics and chemistry.
  • Biological organization arises from atoms forming molecules, which then form cells.
  • Emergent properties appear at higher levels of biological hierarchy.

Elements, Compounds, and Essential Elements

  • Matter consists of elements (pure substances) and compounds (fixed ratio combinations of elements).
  • There are 92 naturally occurring elements; 25 are essential for humans.
  • Four elements (O, C, H, N) make up 96% of living matter; Ca, P, K, S contribute most of the remaining 4%.
  • Trace elements are needed in small amounts (e.g., Fe, I).

Atomic Structure and Isotopes

  • Atoms, the smallest units of elements, consist of protons, neutrons, and electrons.
  • Atomic number equals the number of protons; mass number is protons + neutrons.
  • Isotopes are atoms of an element with different neutron numbers; some are radioactive and used in research and medicine.

Electron Configuration and Chemical Behavior

  • Electrons are arranged in shells; outermost shell electrons (valence electrons) determine chemical behavior.
  • Atoms are most stable with full valence shells; those with incomplete shells are reactive.
  • Orbitals describe electron positions; each can hold two electrons.

Chemical Bonds and Molecular Structure

  • Atoms with incomplete valence shells form chemical bonds to achieve stability.
  • Covalent bonds involve sharing electrons; ionic bonds involve electron transfer.
  • Covalent bonds can be nonpolar (equal sharing) or polar (unequal sharing based on electronegativity).
  • Ionic bonds form between positive (cations) and negative (anions) ions.
  • Weak bonds, like hydrogen bonds and van der Waals interactions, are important for biological processes and molecular shapes.
  • The 3D shape of molecules determines their biological functions.

Chemical Reactions and Equilibrium

  • Chemical reactions break and form bonds, rearranging atoms into new compounds.
  • Reactants are starting materials; products are end results.
  • Matter is conserved in reactions; atoms are neither created nor destroyed.
  • Chemical equilibrium occurs when the rates of forward and reverse reactions are equal; some reactions go to completion.

Key Terms & Definitions

  • Element โ€” a substance that cannot be broken down by chemical reactions.
  • Compound โ€” a substance made of two or more elements in a fixed ratio.
  • Atom โ€” the smallest unit of an element, composed of protons, neutrons, and electrons.
  • Isotope โ€” atoms of the same element with different numbers of neutrons.
  • Valence electrons โ€” electrons in the outermost shell, determining chemical reactivity.
  • Covalent bond โ€” a bond formed by sharing electrons between atoms.
  • Ionic bond โ€” a bond formed by the transfer of electrons, creating charged ions.
  • Hydrogen bond โ€” weak attraction between a hydrogen atom and an electronegative atom.
  • Chemical reaction โ€” process of making and breaking chemical bonds to form new substances.
  • Chemical equilibrium โ€” state where forward and reverse reaction rates are equal.

Action Items / Next Steps

  • Review the periodic table for element names, symbols, and atomic numbers.
  • Practice drawing electron shells and Lewis dot structures for simple molecules.
  • Complete any assigned reading or exercises related to chemical bonding and molecular structure.

Great! Here's a step-by-step guide on how to draw your concept map with suggested connections and arrow labels. I'll indicate where to draw arrows from and to, and what the relationship is.


Step-by-Step Concept Map Drawing Guide


1. Start with the central concept:

"The Chemical Context of Life"
Place this in the center of your page.


2. Draw branches from the central concept to these main topics:

  • Matter
  • Atom
  • Electron Configuration
  • Chemical Bonds
  • Molecular Shape and Function
  • Chemical Reactions

3. Expand each main topic with subtopics and connect them:


Matter

  • Draw arrows from "Matter" to:

    • Elements (label arrow: "composed of")
    • Compounds (label arrow: "composed of")
  • From Elements:

    • Arrow to Essential Elements (label: "includes")
    • Arrow to Trace Elements (label: "includes")
  • From Compounds:

    • Arrow to Example: NaCl (label: "example of")

Atom

  • Draw arrows from "Atom" to:

    • Protons (label: "contains")
    • Neutrons (label: "contains")
    • Electrons (label: "contains")
  • From Atom:

    • Arrow to Atomic Number (label: "defined by number of protons")
    • Arrow to Mass Number (label: "sum of protons and neutrons")
    • Arrow to Isotopes (label: "variants with different neutrons")

Electron Configuration

  • Draw arrows from "Electron Configuration" to:

    • Electron Shells/Orbitals (label: "electrons arranged in")
    • Valence Electrons (label: "outermost electrons")
  • From Valence Electrons:

    • Arrow to Chemical Reactivity (label: "determines")

Chemical Bonds

  • Draw arrows from "Chemical Bonds" to:

    • Covalent Bonds (label: "includes")
    • Ionic Bonds (label: "includes")
    • Weak Bonds (label: "includes")
  • From Covalent Bonds:

    • Arrow to Nonpolar (label: "can be")
    • Arrow to Polar (label: "can be")
  • From Ionic Bonds:

    • Arrow to Cations (+) (label: "forms")
    • Arrow to Anions (-) (label: "forms")
  • From Weak Bonds:

    • Arrow to Hydrogen Bonds (label: "includes")
    • Arrow to van der Waals Interactions (label: "includes")

Molecular Shape and Function

  • Draw arrows from "Molecular Shape and Function" to:
    • Determined by Electron Orbitals (label: "shape is")
    • Affects Biological Function (label: "shape")
    • Molecular Mimicry (label: "similar shapes cause")

Chemical Reactions

  • Draw arrows from "Chemical Reactions" to:
    • Reactants (label: "start with")
    • Products (label: "form")
    • Matter Conservation (label: "obey")
    • Chemical Equilibrium (label: "can reach")

Optional: Connect related concepts across branches

  • From Valence Electrons (Electron Configuration) โ†’ Chemical Bonds (label: "involved in")
  • From Chemical Bonds โ†’ Molecular Shape and Function (label: "influences")
  • From Chemical Reactions โ†’ Chemical Bonds (label: "break and form")

Summary of drawing flow:

  • Central node: The Chemical Context of Life
  • Branch out to 6 main topics
  • Each main topic branches to subtopics with labeled arrows
  • Cross-links between related concepts for deeper understanding

If you want, I can help you create a text-based version with indentation or a list of nodes and edges for software like CmapTools or MindMeister. Would that be helpful?