Fundamental Health Podcast with Dr. Paul Saladino

Host Introduction

• Host: Dr. Paul Saladino
• Focus: Understanding and correcting the roots of chronic disease to live a healthy and radical life.
• Recording from San Diego.

Episode Overview

• Guest: Dr. Ben Lynch, expert in methylation and genetics.
• Known for work on MTHFR gene and nutrigenomics.
• Author of "Dirty Genes" and president of Seeking Health company.

Dr. Ben Lynch's Background

• Best-selling author, leader in nutrigenomics.
• Educational background: B.Sc. in Cell and Molecular Biology, Doctor of Naturopathic Medicine.
• Known for innovative approaches in genetics and health.

Key Topics Discussed

Methylation

• Methylation is crucial for turning genes on and off.
• Involves adding methyl groups (carbon + hydrogen) to molecules.
• Affects over 300 enzymatic reactions in the body.

MTHFR Gene

• MTHFR is crucial for converting dietary folate into methylfolate.
• Variants can lead to reduced enzyme activity affecting methylation.
• Importance of riboflavin for MTHFR function.

Homocysteine and Methylation

• Homocysteine is a byproduct of methylation reactions.
• High homocysteine levels can indicate methylation issues.
• Importance of balancing methionine and glycine intake.

Supplements and Diet

• Supplements are meant to be supplemental to a nutrient-rich diet.
• Seeking Health provides high-quality, intentional supplements.
• Importance of diet rich in organ meats (liver) and nutrients.

Personal Insights

• Dr. Lynch shares personal experiences with methylation and diet interventions.
• Emphasizes the importance of a well-constructed diet and lifestyle.

Practical Takeaways

• Check homocysteine levels to gauge methylation efficiency.
• Consider dietary sources of methyl donors like liver and leafy greens.
• Consider riboflavin intake through diet or supplements if needed.

Closing Thoughts

• Dr. Paul Saladino emphasizes a diet based on first principles.
• Encourages understanding nutrient dense foods and minimizing toxins in diet.

Additional Resources

• Book: "Dirty Genes" by Dr. Ben Lynch.
• Websites: Seeking Health for supplements and educational resources.

These notes cover the key points from the podcast episode with Dr. Ben Lynch on methylation and its impact on health. They emphasize the importance of understanding genetic variations like MTHFR and the role of diet and supplements in optimizing health.