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Thermodynamics in Biology

Jun 5, 2025

Overview

This lecture explains the first and second laws of thermodynamics and their importance in biological systems, especially regarding energy transfer, transformation, and entropy.

Thermodynamics and Biological Systems

  • Thermodynamics studies energy and how it is transferred involving matter.
  • A system includes the matter under study; everything else is the surroundings.
  • Open systems exchange energy and matter with surroundings; closed systems exchange only energy.
  • Biological organisms are open systems, constantly exchanging energy with their environment.
  • The laws of thermodynamics govern energy transfers in all systems, including living organisms.

The First Law of Thermodynamics

  • The first law states the total energy in the universe is constant.
  • Energy cannot be created or destroyed, only transferred or transformed.
  • Energy transformations commonly seen: electrical to light (bulbs), chemical to heat (gas stove), light to chemical (photosynthesis).
  • Cells transform chemical energy from food into ATP, which powers cellular work like movement and molecule synthesis.

The Second Law of Thermodynamics

  • The second law states that no energy transfer is completely efficient; some energy is always lost as unusable heat.
  • Heat energy is energy transferred that does not do work, often due to friction or inefficiencies.
  • Living organisms rely on constant energy input, since energy losses increase system disorder.
  • The measure of disorder or randomness in a system is called entropy.
  • As energy is lost to the surroundings, entropy increases in those surroundings.

Entropy in Physical and Biological Systems

  • High entropy means high disorder and low available energy; low entropy is high order.
  • Living things require energy to maintain low entropy (order) against the natural trend toward disorder.
  • Physical examples: ice (low entropy, molecules fixed), water (higher entropy, molecules move), gas (highest entropy).
  • All energy transfers and chemical reactions in cells increase the universe’s overall entropy.

Key Terms & Definitions

  • Thermodynamics — the study of energy and its transfer in physical matter.
  • System — the matter under study in energy transfer.
  • Surroundings — everything outside the system.
  • Open system — exchanges both energy and matter with surroundings.
  • Closed system — exchanges only energy, not matter, with surroundings.
  • First Law of Thermodynamics — energy cannot be created or destroyed, only transferred or transformed.
  • Second Law of Thermodynamics — every energy transfer increases the universe’s entropy.
  • Entropy — a measure of disorder or randomness in a system.
  • ATP (Adenosine Triphosphate) — molecule that stores and transfers energy in cells.

Action Items / Next Steps

  • Review the concepts of entropy and both laws of thermodynamics.
  • Conduct the suggested experiment: observe ice melting and boiling to see changes in entropy.
  • Read next section on ATP for deeper understanding of energy use in cells.