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Blood Transfusion Procedure

Jun 9, 2025

Overview

This lecture demonstrates the steps for safely administering a blood transfusion, including preparation, verification, setup, monitoring, and handling potential transfusion reactions.

Pre-Transfusion Preparation

  • Ask the patient about previous transfusion reactions.
  • Ensure the patient has a patent (working) IV site.
  • Confirm there is a signed informed consent in the patient's chart.
  • Gather supplies: blood administration Y tubing and normal saline for priming.
  • Prime the tubing with normal saline only, never with other fluids.
  • Connect the primed tubing to the patient's IV and have it ready before retrieving blood.

Blood Verification & Setup

  • Retrieve blood from the blood bank and visually inspect it for correct color, consistency, and intact bag.
  • Two registered nurses must verify: patient identity, blood type, blood unit number, birth date, and cross-matching documentation.
  • Both nurses sign and initial verification documentation.
  • Take and document the patient's initial vital signs before transfusion begins.

Administering the Transfusion

  • Hang the blood bag and spike it to the blood administration tubing.
  • Clamp the saline line when administering blood to prevent backflow.
  • Use the pump to flush out the saline and fill the tubing with blood before starting the official transfusion.
  • Blood transfusion must begin within 30 minutes of receiving blood from the lab, and finish within 4 hours.
  • Official transfusion start time is when blood reaches the patient.

Monitoring and Managing Reactions

  • Stay with the patient for the first 15 minutes to monitor for transfusion reactions.
  • If a reaction occurs, stop the blood infusion immediately and administer normal saline through a separate line.
  • Disconnect and send all blood products and tubing back to the lab for analysis if a reaction occurs.
  • Take a second set of vital signs after 15 minutes if no reaction has occurred.

Key Terms & Definitions

  • Blood transfusion — administration of donated blood products to a patient via IV.
  • Y tubing — specialized tubing with two arms for blood and saline, used for transfusions.
  • Cross-matching — lab process to ensure compatibility between donor blood and recipient.
  • Transfusion reaction — adverse response by the patient’s body to transfused blood.

Action Items / Next Steps

  • Document all verifications, vital signs, and responses in the patient's chart.
  • Remain with the patient for at least the first 15 minutes of the transfusion.
  • Send all materials back to the lab if a transfusion reaction occurs.