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Basics of Embryogenesis and Germ Layers

May 5, 2025

Embryogenesis and Germ Layer Development

Introduction

  • Gastrulation: A key process in early embryogenesis leading to the formation of three primary germ layers.

Three Primary Germ Layers

  1. Endoderm
    • Forms the gastrointestinal tract (GI tract).
    • Develops into structures such as:
      • Lungs (from the upper GI tract)
      • Liver
      • Pancreas
      • Esophagus
      • Stomach
      • Small intestines
      • Large intestines
  2. Mesoderm
    • Forms some inner layers of the skin.
    • Develops into:
      • Muscles, including cardiac muscle
      • Bones
      • Kidneys
      • Bladder
      • Ovaries/Testes
  3. Ectoderm
    • Forms the outer layer of skin.
    • Develops into skin-related structures such as:
      • Sweat glands
      • Hair
    • Also forms the nervous system.

Summary

  • Endoderm: Develops into the gastrointestinal and pulmonary systems including lungs and GI tract organs.
  • Mesoderm: Develops into muscles, heart muscle, skeletal system, and genitourinary tracts.
  • Ectoderm: Develops into skin, related structures, and the nervous system.