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Disaccharides Overview

Jun 13, 2025

Overview

This lecture introduces disaccharides, focusing on their structure, formation, examples (sucrose and lactose), and the role of enzymes in their digestion.

Disaccharides: Structure and Formation

  • Disaccharides are carbohydrates made of two monosaccharides bonded together.
  • Common disaccharides include sucrose (table sugar) and lactose (milk sugar).
  • The bond joining two monosaccharides is called a glycosidic linkage.
  • Disaccharides form by a condensation reaction, releasing a water molecule.
  • Breaking apart disaccharides into monosaccharides is called hydrolysis, which uses up a water molecule.

Sucrose

  • Sucrose is a disaccharide formed from glucose and fructose.
  • Found naturally in plants; common source is table sugar.
  • Sucrose is mainly extracted from sugar cane and sugar beet plants.
  • Diagrammatically, sucrose consists of a six-membered ring (glucose) and a five-membered ring (fructose) joined together.

Lactose

  • Lactose is a disaccharide composed of glucose and galactose.
  • It is found in dairy products and makes up 2-8% of milk.
  • Many cheeses and yogurts have less lactose because bacteria consume it during processing.
  • Lactose consists of two six-membered rings (glucose and galactose) joined together.

Enzymes and Lactose Intolerance

  • Enzymes are proteins that help break down disaccharides into monosaccharides.
  • Lactase is the enzyme that breaks down lactose; sucrase breaks down sucrose.
  • Lactose intolerance occurs when the body lacks lactase, making digesting lactose difficult.

Key Terms & Definitions

  • Disaccharide — a carbohydrate made from two monosaccharides bonded together.
  • Monosaccharide — the simplest form of carbohydrate (e.g., glucose, fructose, galactose).
  • Glycosidic linkage — the bond that joins two monosaccharides in a disaccharide.
  • Condensation reaction — a chemical reaction that joins two molecules and releases water.
  • Hydrolysis — a reaction that breaks a bond using water.
  • Enzyme — a protein that speeds up chemical reactions in the body.
  • Lactase — an enzyme that breaks down lactose.
  • Lactose intolerance — inability to digest lactose due to lack of lactase.

Action Items / Next Steps

  • Research and answer the 10 questions about lactose intolerance in your notes.
  • Show your completed work to the teacher for review.