Overview of Macromolecules

Aug 12, 2025

Overview

This lesson covers macromolecules, their building blocks (monomers and polymers), and explains the four main types: carbohydrates, lipids, proteins, and nucleic acids.

Macromolecules: General Concepts

  • Macromolecules are large molecules essential to all living organisms.
  • They are made of small units called monomers, which join together to form chains called polymers.
  • The four main types of macromolecules are: carbohydrates, lipids, proteins, and nucleic acids.

Carbohydrates

  • Carbohydrates are the main energy source for most living things and provide structure for many plants.
  • Their monomers are called monosaccharides, which are simple sugars like glucose, fructose, and ribose.
  • Chains of monosaccharides are called polysaccharides.
  • Examples of polysaccharides:
    • Starch (energy storage in plants)
    • Glycogen (energy storage in animals)
    • Cellulose (structure in plants)
    • Chitin (structure in insects)

Lipids

  • Lipids include fats, phospholipids, and steroids, and are all hydrophobic.
  • Functions include energy storage, forming cell membranes, and acting as hormones.
  • Lipids do not have true monomers, but include:
    • Triglycerides (fats)
    • Saturated and unsaturated fats
    • Phospholipids (form cell membranes)
    • Steroids (such as cholesterol and sex hormones)

Proteins

  • Proteins are involved in nearly all cellular functions and are major components of living organisms.
  • Their monomers are amino acids, with 20 different types.
  • Chains of amino acids are called polypeptides.
  • The function of a protein depends on how it folds.

Nucleic Acids

  • Nucleic acids store, transmit, and express genetic information.
  • Their monomers are nucleotides (such as adenine, guanine, and thymine).
  • Chains of nucleotides are called polynucleotides, which make up DNA and RNA.

Key Terms & Definitions

  • Macromolecule — a large molecule made of smaller units (monomers).
  • Monomer — a small building block that can join with others to form a chain.
  • Polymer — a chain of monomers.
  • Monosaccharide — a single sugar molecule, building block of carbohydrates.
  • Polysaccharide — a chain of many monosaccharides.
  • Amino acid — building block of proteins.
  • Polypeptide — a chain of amino acids that forms proteins.
  • Nucleotide — building block of nucleic acids.
  • Polynucleotide — a chain of nucleotides (e.g., DNA, RNA).

Actions / Next Steps

  • Watch the suggested video about DNA and RNA for more information.
  • Look for videos on each type of macromolecule as they become available.