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Introduction to Biochemistry

Aug 6, 2025

Overview

This lecture introduces biochemistry, covering its definition, history, key applications, and relevance to daily life and health.

Introduction to Biochemistry

  • Biochemistry is the study of the chemical processes in living organisms.
  • It explores how cells function, what they are composed of, and the chemical reactions within them.
  • DNA and RNA interactions are vital to cell creation and functioning.

Historical Background

  • In 1833, German physiologist Albert Juan Cole Licker used chemistry to explain cellular functions for the first time.
  • The study of biochemistry has evolved to uncover how life developed and how proteins reveal evolutionary relationships.

Applications and Everyday Impact

  • Biochemistry is essential in developing medicines and treatments for diseases like cancer and diabetes.
  • It helps analyze environmental pollution and its effects.
  • Biochemistry aids in understanding genetic diseases by analyzing human DNA.
  • Research into ancient fossils helps discover the origins of life.
  • Biochemistry explains the function of proteins in living cells and their roles in health (e.g., blood plasma proteins).

Areas of Biochemical Study

  • Computational biology focuses on how proteins fold into functional shapes.
  • Microbial genomics studies microorganisms in various environments.
  • Lipidomics studies the role of fats in cells.
  • Proteomics investigates protein structure, function, and expression.
  • Cell signaling examines molecules controlling cell survival and death.

Relevance and Benefits of Studying Biochemistry

  • Biochemistry provides insights into molecular health issues such as obesity and diabetes.
  • Biochemists develop treatments for diseases like HIV/AIDS, cancer, and Lyme disease.
  • Biochemical engineering supports the development of biodiesel and food additives like artificial sweeteners.
  • There is overlap with molecular biology for high-resolution study of biological molecules.

Key Terms & Definitions

  • Biochemistry — the science of chemical processes within and related to living organisms.
  • DNA/RNA — genetic materials that store and transfer information.
  • Protein — complex molecules crucial for cellular structure and function.
  • Proteomics — the study of all proteins in a cell or organism.
  • Cell Signaling — communication processes that control cell activities.

Action Items / Next Steps

  • Visit themasterchemistry.com for additional learning resources.
  • Subscribe to the indicated YouTube channel for further video lectures.