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Thin Layer Chromatography of Photosynthetic Pigments

May 29, 2024

Thin Layer Chromatography of Photosynthetic Pigments

Sample Preparation

  • Crushing the Plant Sample: Use a pestle and water to break the cell wall and membranes, releasing photosynthetic pigments from chloroplasts.
  • Chloroplast Membrane: Needs to be broken to release pigments.

Application to Chromatogram

  • Stationary Phase: Silica gel on plastic; handle with care to avoid contamination.
    • Silica Gel: Despite being called a gel, it's dried on plastic.
  • Pencil Line: Drawn with pencil to avoid dissolution by the solvent.
  • Pigment Application: Apply pigment mixture as a small dot on the line.
    • Allow it to dry between applications.
    • Typically repeated about 10 times for concentration.

Developing the Chromatogram

  • Mobile Phase: Solvent that dissolves pigments and moves them up the chromatogram.
    • Ensure solvent is below pencil line to prevent pigments from dissolving directly into solvent.
    • Smaller pigments travel further up due to less resistance in silica gel.

Calculating Rf Values

  • Distance Calculation:
    • Distance moved by pigment (compound) / Distance moved by solvent front.
    • Measure in millimeters for accuracy.
  • Comparison with Known Values: Match calculated Rf value with standard Rf values to identify pigments (e.g., Rf value of 0.42 might indicate Chlorophyll b).

Exam Preparation

  • Ability to estimate pigment identity from chromatogram.
  • Accurate calculation of Rf values.