hey I'm Melanie King it from the absolute recap and today's video is going to recap AP biology unit one chemistry of [Music] life this video is not only going to help you study for your unit tests but your midterm exams final exams and most importantly the AP biology exam in May before I start click down in the description below so you can get your free copy of the AP Bio unit 1 ultimate review packet this packet includes a unit one video study guide with answer key practice multiple choice questions Skills Practice sheets with video explanations podcast and video resource links and an frq task for a breakdown if you're taking a non-ap biology class either in high school or college these resources can absolutely help you too now you'll get the most out of this unit one recap video with active practice and participation so I recommend you print the accompanying PDF study guide and pause the video periodically to complete the practice questions and guided notes for each section I'm going to go through the topics fairly quickly because the goal of this video is to help you dust off the concept cobwebs so that you can start to make connections at the end of the video you'll want to check your study guide responses using my answer key and then go back to rewatch any areas that gave you trouble all right listen I know it's tempting to cut corners but if you skip right to the answer key and you never try the questions first yourself then you aren't utilizing this video and the ultimate review packet to its fullest and I want you to gain that confidence in biology so that you can do your absolute best in your class and on assessments so no peeking at that answer key until later if you're getting confused throughout the video on some of the individual Concepts and you need more information check out the absolute recap biology Edition podcast and our YouTube channel for help this summary video is going to review all of the main unit one topics according to the College Board curriculum you can use these timestamps listed here to Jump Ahead or go back to a specific subtopic at any time all right let's zoom out I know this is biology but we have to start with the foundation in chemistry if we don't focus on the microscopic first then nothing that happens on the macroscopic level will make any sense a strong understanding on what influences the chemical behavior of an atom will help you draw connections between molecular structure and function and make predictions for cellular processes every organism needs to obtain energy and exchange matter with the environment so let's start with an introduction to water and review the most common elements and reactions for life then I'll recap the four groups of biological molecules carbohydrates proteins lipids and nucleic acids which will make many appearances in all eight units of AP Bio let's zoom in water might be the most amazing molecule on Earth and it can defy gravity how well I'll tell you but we need to sketch it out first good old H2O two elements of hydrogen for every element of oxygen form with polar calent bonds oxygen is more electron negative and has more pull on the shared electrons with hydrogen consequently oxygen has a partial negative charge while each hydrogen atom has a partial positive charge this uneven distribution of Charge results in a polar molecule of water that makes life possible if we can recall our chemistry background we know that opposite charges attract and like charges repel because water is polar it will attract to and bond with other polar or charge molecules even earning the title the universal solvent in fact almost all of water's unique properties are due to its polarity and ability to form hydrogen bonds because opposite charges attract a hydrogen bond forms between a partial positive hydrogen of one water molecule and a partial negative oxygen of another water molecule when we look at water as a collective we'll find hydrogen bonds forming between adjacent water molecules and polar calent bonds forming within water molecules hydrogen bonding is the foundation by which water molecules interact with other things in liquid water hydrogen bonds are continuously breaking and reforming boiling water has to break those hydrogen bonds in order to cause the water molecules to move more rapidly which is why water has a high specific heat however when water freezes the hydrogen bonds become more stable and the water molecules get pushed farther apart in less dense this is why ice floats on water the three big properties of water you need to know for the exam are adhesion cohesion and surface tension water is attracted to water called cohesion and to other polar or charged things called adhesion both cohesion and adhesion give water its remarkable ability to defy gravity let's look at a plant water moves vertically from the roots to the leaves through adhesion to the walls of plant vasculature and cohesion to other water molecules as transpiration occurs at the leaves there is a barrel of monkey action in which water molecules pull up on the water molecule below it you might have also seen this gravity defying stunt in a graduated cylinder during lab a meniscus forms the bottom curve of a graduated cylinder because the forces of adhesion to the glass are stronger than cohesion between water molecules water literally jumps up the sides water also has remarkable surface tension due to cohesive and adhesive forces Es as seen in a droplet of water or Morning Dew that forms on a blade of grass surface tension is also why certain insects can literally walk on water the interaction their body has with the water is weaker than the hydrogen bonds between the water molecules themselves organisms must exchange matter with the environment to grow reproduce and keep themselves organized quick Science Background review matter is made up of atoms has mass and takes of space for example rocks Tre trees and people are made of matter while energy is not atoms contain three subatomic particles protons are positively charged found in the nucleus and are represented as the atomic number on the periodic table neutrons have no charge and are also found in the nucleus electrons have a negative charge and are found surrounding the nucleus in rings because electrons are the most peripheral of the three subatomic particles they will be involved in bonding with other atoms metabolism is the sum of all chemical reactions that take place within an organism those that are bond breaking or catabolic and those that are Bond forming or anabolic we have to do both to be biologically successful when organisms obtain matter they can use the raw materials to build useful molecules for biological processes for example organisms taken glucose as a reactant for cellular respiration and carbon dioxide for photosynthesis what do you think of when you hear the word organic images might come to mind of apples grown without pesticides or grass-fed cows but in science organic molecules contain car carbon because carbon has four veence or outer ring electrons it forms four calent bonds with other elements these bonds can be single double or triple causing molecular shapes of straight chains Branch chains and Rings carbon is so versatile the six most common elements found in living things are carbon hydrogen nitrogen oxygen phosphorus and sulfur carbon hydrogen and oxygen are represented in all biological molecules nitrogen will never be found in in carbs and lipids but is always a component of nucleic acids in their nitrogenous base and proteins and the amino group even though nitrogen is the most abundant gas in the atmosphere it will need to be taken in through food or absorbed from the soil the final two elements make infrequent appearances phosphorus will always be in nucleic acids as a component of the backbone of DNA and it will appear in lipids that are phospholipids the presence of a phosphate group gives DNA a negative charge and phospholipid heads they polarity and subsequent hydrophilic Affinity sulfur makes its only appearance in some R groups of proteins and influences protein folding through the formation of disulfide bridges water is a key player in two of our primary chemical reactions of metabolism dehydration reactions are used to join monomers together and form a larger polymer it's exactly as described to dehydrate to take out water so if you link two adjacent monomers you can pull hydroxy from water end and a hydrogen off of the other removing H2O the electrons left behind on those monomers are now available to Coal bond together in contrast hydrolysis reactions add water to break a polymer into monomers when this occurs we stick a hydroxy onto one monomer and a hydrogen onto the other the remaining three sections of unit one cover the four biological macro molecules and properties structures and functions instead of jumping back and forth for each type Within sections 1.4 1.5 and 1.6 I'm going to review each Macro Molecule individually beginning with proteins then carbohydrates lipids and lastly nucleic acids proteins are polymers formed from amino acid monomers an amino acid is made up of one Central carbon atom that forms four single calent bonds one is to hydrogen another is to an acidic carboxy group and a third is to a basic amino group the fourth calent bond is to an R Group which is a substitute for different side chains that give each of the 20 different amino acids their unique chemical properties these properties could be hydrophobic hydrophilic or even ionic when amino acids link together dehydration synthesis occurs between an amino group of one monomer and the carboxy group of the other the calent bond formed between them is referred to as a peptide bond and when you get many peptide bonds in a row you formed a poly peptide polypeptide chains the primary structure of proteins are formed during the process of translation at a ribosome in UK carots the newly synthesized polypeptide is released for further processing by the rough endoplasmic reticulum and shipping by the Gogi body several scientists were initially convinced that proteins were the molecule of heredity not DNA it made sense they have more alphabet in their chemistry than its counterpart DNA with 20 amino acids as compared to four nitrogenous bases and you can form a lot more diverse structures for a multitude of functions with proteins than you can with DNA proteins have four levels of structure as it bends and folds in upon itself one wrong amino acid and the protein folding will be incorrect potentially causing an error in function primary structure is a chain of amino acids from the N Terminus to the C Terminus secondary can either form an alpha helix or a beta pleated sheet through local folding from backbone hydrogen bonding tertiary structure has a specific 3D shape when Alpha helices and beta sheets fold further inwards due to R Group bonding interactions the final level of structure is quinary which has two or more separate amino acid chains interacting and bonding together the specific structure that each protein has is dependent upon the chemical properties of the R Group and can be influenced by environmental factors R Group side chains that are hydrophilic or charged fold outward toward the aquous environment while those that are hydrophobic face the interior ior of the protein protein structure denatures when hydrogen bonds are disrupted this shape change directly affects the protein's function and can sometimes be reversed since primary protein structure is not changed proteins practically do everything for the cell and even this impressive list I'll discuss now is incomplete they are a key component in cellular membranes with roles in transport recognition movement and communication integral membrane proteins have hydrophobic regions that interact with phosph popid tails and hydrophilic regions that are adjacent to the heads some integral proteins have specific molecular chemistry internally forming a channel these channels may be gated and allow specific ions or small molecules to cross the membrane through facilitated diffusion or active transport peripheral proteins like hormones and antigens they're more Loosely attached to the membrane and are involved in cell recognition and communication membrane proteins can also provide anchorage for the cytoskeleton aing in structural support and cellular movement and lastly proteins also form enzymes that catalyze chemical reactions for specific substrates for example the enzyme sucra has a specific active site which fits the substrate sucrose a disaccharide this enzyme facilitates the hydrolysis reaction of sucrose into monomers glucose and fructose carbohydrates only contain the elements carbon hydrogen and oxygen in a 1:2:1 ratio they are polysaccharide formed from monosaccharide monomers which join to other monosaccharides with a specific type of calent bond called a glycidic linkage these biological molecules can form long chains or ringed structures formed by autot tropes and disassembled by nearly all living things carbohydrates are the primary source of chemical energy for the cell and serve as structural material monosaccharides like glucose and fructose as well as disaccharides such as lactose and sucrose are often used as fuel sources for the cell glucose C6 h126 takes the main stage in AP Bio during cellular respiration in the mitochondria and photosynthesis in the chloroplast larger polysaccharides such as cellulose in plant cell walls and kiten and animal exoskeletons can be used for structural support the polysaccharides starch and glycogen are used for long-term energy storage in plants and animals respectively the primary contrast and types of polysaccharides is in their glycosidic linkage branching patterns and functions many carbs look like chemical twins at First Sight but organisms can tell the difference glucose has an identical chemical formula to the isomer fructose and galactose but its atoms are arranged differently starch and cellulose are both formed from consecutive glucose monomers but have varying linkage at the 1 14 Bond even these small differences are enough for enzyme substrate specificity which is why glucose is used for cellular respiration not fructose and animals can digest starch but not cellulose lipids are very diverse group of hydrophobic molecules that are non-polar due to their hydrocarbon chains they contain the elements carbon hydrogen and oxygen and sometimes phosphorus when forming membranes unlike carbohydrates lipids have a ratio of hydrogen to oxygen that is much greater than 2: 1 instead of an elemental ratio of 1: 2: 1 like carbs you could say one to two to few additionally lipids don't have a true monomer as there's no structural pattern of repeating units the different lipid varieties fats phospholipids and steroids all have unique structures for specific roles within organisms fats contain a glycerol and long hydrocarbon fatty acid chains a saturated fatty acid is named for a literal Elemental saturation of hydrogens if all electrons within a hydrocarbon chain are occupied with single bonds to hydrogen then the fatty acid tails are straight and more closely packed together if the fatty acid chains are unsaturated that means there's at least one carbon to carbon double bond and a resulting Bend in the fatty acid chain in this circumstance the Tails cannot be closely packed together and are less dense put Three fatty acid chains with glycerol and you have the fat triglyceride an important energy source attach long fatty acid chains to alcohol and you get waxes lipids that play a role in water Reg potion of plants and animals perhaps the most common lipid or common to AP Bio at least is the phospholipid phospholipids are amphipathic with two hydrophobic fatty acid tails and a hydrophilic head the hydrophilic head has a glycerol a modified phosphate group and often a Coline group the properties of phospholipids and their nature of forming a bilayer makes them the ideal molecule to make up all cellular membranes because the intracellular and extracellular environments are aquous membranes are B layered with Tails facing inwards this allows certain cells and membrane bound organel to compartmentalize their functions additionally different types of phospholipids in cell membranes allow the organism's flexibility to adapt to different environmental temperatures lastly steroids which have four fused carbon rings with attached functional groups they look very different from any other lipid with hydrocarbon chains but they'll still be non-polar and hydrophobic you can find steroids in cell membranes like cholesterol as well as with signaling molecules like hormones genetic information is transmitted from one generation to the next through DNA or RNA both of these polymers are examples of nucleic acids which are made of monomers called nucleotides a nucleotide has three parts a pentos sugar a phosphate group and a nitrogenous base all coal bonded together nucleic acids have a linear sequence with directionality designated as five Prime on the phosphate side of the sugar and three Prime on the hydroxy side of the sugar it is important to recognize that double stranded DNA is anti-parallel meaning that one side of the backbone is oriented 5 Prime to 3 Prime while the Strand across fromit is 3 Prime to 5 Prime directionality will be very important when discussing molecular orientation and enzyme binding during processes such as replication transcription and translation the difference between DNA and RNA sugars occurs at the two prime carbon RNA has ribos which contains a hydroxy group at the two prime carbon DNA has deoxy ribos which is missing the oxygen at the two prime carbon a nucleotide phosphate group is calent bound to the five Prime carbon of the Pento sugar within a nucleotide and to the three prime carbon of the pentos sugar of an adjacent nucleotide alternating sugars and phosphates form the backbone of each nucleic acid through the formation of a specific type of calent bond called a phospher bond the phosphate group has a negative charge which is why DNA samples migrate towards the cathode side during gel electropheresis phosphate groups are the same in RNA and DNA the last part of a nucleotide is the nitrogenous base which encodes the genetic information the nitrogenous base is arranged perpendicular to the backbone and cently bonded to the pentos sugar at the one prime carbon there are five different types of nitrogenous bases grouped into two categories the purines are double ringed nitrogenous bases and include guanine and Adine these are found in both DNA and RNA molecules the peridin are single ring nitrogenous bases and includes cytosine thyine and uracil cytosine is common to both nucleic acids whereas thyine is only in DNA and urasil is only an RNA adenine will always bond with thyine or uracil with two hydrogen bonds and guanine will always bond with cytosine with three hydrogen bonds to recap water is an amazing molecule whose polarity influences hydrogen bonding and all of its properties like cohesion adhesion and surface tension water is formed through dehydration reactions and added when dividing polymer chains during hydrolysis reactions organic molecules are made of carbon and form a variety of structures through bonding patterns with the elements hydrogen nitrogen oxygen phosphorus and sulfur organisms obtain these elements from their environment and metabolize polymers to grow reproduce and maintain organization the four major biological molecules are carbohydrates proteins lipids and nucleic acids carbohydrates are formed from monosaccharides and provide energy and structural support proteins are polypeptides made of amino acids which fold into specific shapes through hydrogen bonding in our group interactions lipids are non-polar hydrophobic molecules including fats phospholipids and steroids and nucleic acids are the molecule of heredity with directionality formed from nucleotide monomers pH we made it a full recap of AP biology unit 1 chemistry of life and now it's time for you to practice applying this information if you haven't already grabbed your free copy of the AP biology unit 1 ultimate review packet what are you waiting for click the link in the description below now trust me it's the ultimate way for you to do your absolute best in your biology class and on the AP biology exam in may now if you've already finished the unit one study guide for this video then definitely check your responses with my answer key to verify your understanding for all the different concepts you can access these answers for free in the ultimate review packet then you'll want to take the unit one practice multiple choice questions where you'll get instant feedback on your answers and an explanation for why the answers are correct and why the other choices weren't these are also free if you want more answers for unit one as well as practice for unit 2 through 8 so you can be ready for the AP Bio exam then make sure to purchase the AP biology ultimate review packet it has unit specific skills videos practice sheets and a ful length practice exam that you can take once you finish the entire course thank you so much for watching and supporting my content please make sure to subscribe to my YouTube channel like these videos and tell your friends about the ultimate review packet I'll see you next recap for unit 2 cell structure and function