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Bone Histology Overview

Sep 22, 2025

Overview

This lecture covers the microscopic structure (histology) of bone tissue, focusing on the differences between compact and spongy bone and their structural features.

Compact Bone Structure

  • Compact bone forms the hard, outer layer of bones and resists stress and strain.
  • Compact bone is organized into cylindrical units called osteons.
  • Each osteon consists of 4 to 20 concentric rings called lamellae (singular: lamella).
  • Collagen fibers in the lamellae run in alternating directions in each layer for added strength.
  • The central canal (Haversian canal) runs down the center of each osteon and contains blood vessels and nerves.
  • Osteocytes (bone cells) live in small cavities called lacunae (singular: lacuna) within the lamellae.
  • Lacunae are connected by tiny canals called canaliculi, allowing osteocytes to communicate and share resources via gap junctions.
  • Bone is dynamic, with osteoclasts breaking down bone and osteoblasts building new bone, leaving behind interstitial lamellae between osteons.
  • Circumferential lamellae are found on the outer and inner surfaces of compact bone, adding overall strength.
  • Perforating (Volkmann's) canals run perpendicular to central canals, connecting blood vessels from the periosteum to osteons.

Spongy (Trabecular) Bone Structure

  • Spongy bone is found inside bones and is less dense than compact bone, providing support against multidirectional stress.
  • Spongy bone consists of a network of struts called trabeculae, not osteons.
  • Trabeculae are covered by endosteum, which contains osteoblasts for bone formation.
  • Although lamellae and lacunae with osteocytes exist in spongy bone, there are no central or perforating canals.
  • Spongy bone receives its blood supply from vessels in the bone marrow.

Key Terms & Definitions

  • Osteon β€” Cylindrical structural unit of compact bone.
  • Lamella(e) β€” Concentric rings of bone matrix found within osteons.
  • Central Canal (Haversian canal) β€” Channel in the center of an osteon containing blood vessels and nerves.
  • Lacuna(e) β€” Small cavities in bone that house osteocytes.
  • Canaliculi β€” Tiny canals connecting lacunae for cell communication.
  • Interstitial Lamellae β€” Fragments of old osteons found in spaces between new osteons.
  • Circumferential Lamellae β€” Rings of bone matrix surrounding the entire bone beneath the periosteum.
  • Perforating (Volkmann's) Canal β€” Canals running perpendicular to central canals to connect blood supply.
  • Trabecula(e) β€” Struts forming the framework of spongy bone.
  • Periosteum β€” Outer membrane covering bones, containing blood vessels and nerves.
  • Endosteum β€” Membrane lining internal bone surfaces and covering trabeculae.

Action Items / Next Steps

  • Review diagrams of compact and spongy bone structures in your textbook.
  • Study the functions of each bone component for upcoming quizzes.