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Overview of Lipids and Their Functions

Apr 8, 2025

Lecture on Lipids (Chapter 6)

Introduction to Lipids

  • Definition: Lipids, commonly known as fats, are crucial for bodily functions but insoluble in water.
  • Major Groups: Triglycerides, Phospholipids, Sterols.

Triglycerides

  • Structure: Composed of one glycerol molecule and three fatty acids.
  • Role:
    • Primary form of fat storage and energy source.
    • Insulation and protection for the body.
    • Aids in absorption of fat-soluble vitamins.
  • Food Sources: Animal fats, vegetable oils, bakery items, dairy products.

Fatty Acids

  • Chain Lengths: Short, medium, long; affect digestion speed.
  • Types:
    • Saturated: No double bonds, solid at room temperature (e.g., butter, lard).
    • Unsaturated: One or more double bonds, liquid at room temperature (e.g., olive oil).
    • Trans Fat: Result from hydrogenation, solid at room temperature, linked to increased cardiovascular risk.

Phospholipids

  • Function:
    • Main component of cell membranes.
    • Act as emulsifiers, aiding lipid transport in the bloodstream.
  • Structure: Amphipathic with hydrophilic and hydrophobic parts.

Sterols

  • Cholesterol: Essential for cell membranes, hormone production, vitamin D synthesis.
  • Sources: Produced by the body and found in animal-based foods.

Essential Fatty Acids

  • Types: Omega-6 (linoleic acid), Omega-3 (alpha-linolenic acid).
  • Sources: Vegetable oils, nuts, fish, flax, walnuts.
  • Importance: Reduce inflammation, regulate physiological functions.

Hydrogenation

  • Purpose: Adds hydrogen to unsaturated fats, increases shelf life.
  • Consequence: Creates trans fats, linked to increased cholesterol and cardiovascular risk.

Role of Lipids in the Body

  • Energy: Provide 9 kcal per gram, fuel at rest and during exercise.
  • Storage: Stored energy source.
  • Hormones: Involved in hormone production and vitamin absorption.

Guidelines for Fat Intake

  • AMDR: 20-35% of total daily energy; saturated fats should be 7-10%.
  • Hidden Fats: Found in baked goods, fast food; read labels carefully.

Fat Replacers

  • History: Developed to reduce fat content in foods.
  • Issues: May cause digestive problems, not necessarily lower in calories.

Lipid Digestion and Absorption

  • Process: Starts in the mouth, continues in the stomach and small intestine.
  • Bile and Enzymes: Necessary for digestion and absorption.

Lipoproteins and Their Roles

  • Types:
    • VLDLs: Transport triglycerides, levels affected by diet and exercise.
    • LDLs: Deliver cholesterol, high levels linked to heart disease.
    • HDLs: Good cholesterol, removes excess cholesterol, protective role.

Health Concerns

  • Dietary Fat: Essential but high intake increases risk of cardiovascular disease, obesity, certain cancers.
  • Cardiovascular Disease: Leading cause of death; linked to high fat intake, lifestyle factors.
  • Prevention: Reduce saturated and trans fat intake, increase physical activity, fiber intake.

Conclusion

  • Balance and moderation in diet are crucial.
  • Understanding labels and dietary guidelines can help manage fat intake effectively.