Electrophysiology Study Overview

Jul 25, 2025

Overview

This lecture covers the indications for an electrophysiology (EP) study, key arrhythmias, EP lab equipment, catheter placement, procedural steps, and potential risks.

Indications for EP Study

  • EP studies are recommended when symptomatic arrhythmias are documented on ECG and further evaluation is needed.
  • Indications include bradyarrhythmias (slow rhythms), tachyarrhythmias (fast rhythms), and for planning/performing ablation procedures.
  • EP studies are typically performed in patients with unexplained syncope, suspected structural heart disease, or survivors of sudden cardiac death.

Bradyarrhythmias

  • Bradyarrhythmias involve slow heart rates due to problems with impulse generation (SA node issues) or impulse propagation (AV block).
  • SA node dysfunction may present as sinus bradycardia, sinus pauses, arrest, or sick sinus syndrome.
  • AV block can be within the AV node (often reversible) or below it (usually requires a permanent pacemaker).

Tachyarrhythmias and Ablation

  • Tachyarrhythmias such as supraventricular tachycardia (SVT), Wolff-Parkinson-White (WPW), and ventricular tachycardia (VT) are evaluated with EP studies.
  • Ablation procedures aim to eliminate sources of arrhythmia, especially atrial fibrillation and atrial flutter.

EP Lab Equipment and Catheter Placement

  • EP catheters are insulated wires with distal electrodes for recording or pacing, connected to an external junction box.
  • Common catheters: High Right Atrium (HRA), His Bundle (H), Right Ventricular Apex (RVA), Coronary Sinus (CS), and Radio Frequency (RF) ablation catheter.
  • Placement is typically via the femoral vein under fluoroscopic guidance in a sterile environment.

Recording and Mapping

  • Catheters record intracardiac electrograms (EGMs) to analyze conduction pathways.
  • Signals from different catheters correlate with ECG intervals (e.g., HRA with P wave, H with PR/QRS, RVA with QRS).
  • 3D mapping systems assist in visualizing electrical activity and guiding ablation.

EP Lab Procedure

  • Patient preparation includes consent, fasting, baseline state, discontinuing antiarrhythmic drugs, and possible sedation.
  • Staff includes an electrophysiologist, cardiac nurses, and a technologist, all ACLS-trained.
  • Risks include vascular complications, infection, arrhythmia induction, AV nodal damage, and cardiac tamponade.

Key Terms & Definitions

  • Arrhythmia — abnormal heart rhythm.
  • Bradyarrhythmia — slow heart rhythm.
  • Tachyarrhythmia — fast heart rhythm.
  • Electrogram (EGM) — intracardiac electrical recording.
  • Fluoroscopy — real-time X-ray imaging.
  • Ablation — procedure to destroy arrhythmogenic tissue.
  • Sick Sinus Syndrome — SA node dysfunction causing bradyarrhythmia.

Action Items / Next Steps

  • Review catheter locations and their corresponding ECG/EGM correlations.
  • Read about procedural risks and patient preparation for EP studies.
  • Prepare for upcoming session on catheter placement details.