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Brain 2/4

Aug 13, 2025

Overview

This lecture covers the basic structures, functions, and organization of the cerebrum, the largest and most advanced region of the brain.

Cerebrum Structure

  • The cerebrum consists of two cerebral hemispheres separated by the longitudinal fissure, with the falx cerebri inside.
  • Each hemisphere appears similar anatomically but has some functional differences.
  • Hemispheres operate contralaterally, meaning each side controls the opposite side of the body.

Lobes and Major Cortical Areas

  • The cerebrum is divided into lobes: frontal, parietal, occipital, temporal, and insula (insular lobe).
  • Frontal lobe: contains the primary motor cortex (precentral gyrus) responsible for initiating voluntary skeletal muscle movement.
  • Parietal lobe: contains the primary sensory cortex (postcentral gyrus) for processing touch, pain, temperature, and taste.
  • Occipital lobe: houses the visual cortex for processing visual stimuli.
  • Temporal lobe: processes auditory (hearing) and olfactory (smell) information.
  • Insula: located beneath the lateral sulcus, processes taste (gustatory cortex).

Association Areas and Specialized Functions

  • Association areas help interpret information and plan responses by integrating sensory and motor data.
  • The prefrontal cortex (front of frontal lobe) manages reasoning, judgment, emotions, personality, and decision-making.
  • Broca’s area (frontal lobe) is necessary for speech production; Wernicke’s area (temporal lobe) is needed for speech comprehension.
  • Sensory and motor experiences are given context through nearby association areas.

Hemispheric Specialization and Communication

  • The left hemisphere excels in language, speech, and math; the right in touch and spatial visualization.
  • Association fibers connect regions within a hemisphere; commissural fibers (e.g., corpus callosum) connect the two hemispheres.
  • Projection fibers link the cerebrum to lower brain regions and the spinal cord.

Gray and White Matter

  • Gray matter includes the cerebral cortex and basal nuclei (islands of gray matter deep within the cerebrum).
  • White matter consists of myelinated axons (fibers) transmitting information between brain regions.

Basal Nuclei Function

  • Basal nuclei provide subconscious control of skeletal muscle tone and help coordinate learned movement patterns.

Key Terms & Definitions

  • Cerebrum — largest brain region, responsible for higher functions.
  • Longitudinal fissure — deep groove dividing left and right hemispheres.
  • Gyri (gyrus) — raised ridges on the brain surface.
  • Sulci (sulcus) — shallow grooves between gyri.
  • Association area — cortex region integrating and interpreting sensory/motor information.
  • Prefrontal cortex — region for intellect, reasoning, personality, and emotions.
  • Corpus callosum — main commissural fiber connecting both hemispheres.
  • Basal nuclei — clusters of gray matter within the cerebrum controlling movement.

Action Items / Next Steps

  • Review diagrams of the cerebrum and label the lobes and key cortical areas.
  • Read about the history and function of the prefrontal cortex (optional).
  • Prepare for next lecture on the cerebellum and brainstem.