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Blood Vessel Structure and Function

Jun 23, 2025

Overview

This lecture covers the structure and function of blood vessels, how blood circulates through the body, and the adaptations that support circulation.

Blood Vessel Types and Structure

  • The circulatory system includes arteries, veins, and capillaries, plus smaller arterioles (mini-arteries) and venules (mini-veins).
  • Blood vessels are dynamic organs that actively contract and expand to regulate blood flow and pressure.
  • All blood vessels (except capillaries) have three layers: tunica intima (inner), tunica media (middle), and tunica externa (outer).
  • The tunica intima contains endothelium, a smooth lining that reduces blood friction.
  • The tunica media is made of smooth muscle and elastin, controlling vessel diameter via vasoconstriction and vasodilation.
  • The tunica externa is mostly collagen fiber and provides protection and reinforcement.

Differences Among Vessel Types

  • Arteries carry blood away from the heart; veins return it to the heart; capillaries allow exchange between blood and tissues.
  • Elastic arteries (like the aorta) absorb pressure surges from the heart and recoil to dampen fluctuations.
  • Muscular arteries (like the brachial and radial) distribute blood to specific regions and have the thickest tunica media.
  • Arterioles branch from arteries and feed capillary beds.
  • Capillaries consist of a single epithelial layer (tunica intima) to maximize exchange of oxygen, nutrients, and wastes.
  • Venules collect blood from capillaries and merge into veins.

The Circulatory Circuit and Adaptations

  • Blood moves in a closed loop, starting and ending at the heart; the system contains about five liters of blood.
  • Venous valves, especially in limbs, prevent backflow when returning blood to the heart under low pressure.
  • Damage to vessels can cause visible bleeding or bruising (internal bleeding).
  • Blood pressure and flow are regulated by vessel contraction; form matches function in vessel design.

Capillary Beds and Thermoregulation

  • Capillary beds are networks that regulate blood flow and blood pressure, and play a role in body temperature.
  • Sphincters around capillaries can restrict or allow blood flow to conserve or release heat.

Key Terms & Definitions

  • Artery — blood vessel carrying blood away from the heart.
  • Vein — blood vessel returning blood to the heart.
  • Capillary — tiny vessel for exchange of gases and nutrients with tissues.
  • Tunica intima — innermost vessel layer, in direct contact with blood.
  • Tunica media — middle vessel layer of smooth muscle and elastin.
  • Tunica externa — outer vessel layer, mainly collagen fibers.
  • Vasoconstriction — narrowing of blood vessels by muscle contraction.
  • Vasodilation — widening of blood vessels by muscle relaxation.
  • Endothelium — smooth epithelial lining inside blood vessels.

Action Items / Next Steps

  • Review the three-layer structure of blood vessels and their functions.
  • Study the pathway of blood from the heart through arteries, capillaries, and veins.
  • Understand how vessel adaptations help control blood flow and pressure.