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Feedback Loops Overview

Aug 9, 2025

Overview

This lecture explains the key elements of feedback loops, including their structure and biological examples, to help you understand how systems maintain stable conditions.

Components of a Feedback Loop

  • A feedback loop exists when system output is fed back as input, forming a loop.
  • Key elements: receptor (detects change), effector (acts to correct change), stimulus (change detected), and response (action taken).
  • Receptors and effectors are organs; stimulus and response are actions.

Structure and Pattern of Feedback Loops

  • Feedback loops are often illustrated as figure-eights, with receptors in the center and effectors at the top and bottom.
  • Negative feedback loops keep variables near a set point, correcting deviations.
  • Positive feedback loops amplify changes, moving the system away from a set point.

Feedback Loop Analogy Examples

  • Speed sign example:
    • Eye is the receptor (detects speed); foot is the effector (presses brake or gas).
    • Going too fast (stimulus): slow down (response); going too slow: speed up.
  • Thermostat example:
    • Thermostat is the receptor (senses temperature); furnace is the effector.
    • Room too hot: furnace turns off; room too cold: furnace turns on.

Biological Feedback Loops

  • Thermoregulation:
    • Receptor: hypothalamus in the brain detects body temperature.
    • Effectors when too hot: sweat glands (sweat), capillaries (dilate).
    • Effectors when too cold: capillaries (constrict), muscles (shiver), goosebumps.
  • Blood glucose regulation:
    • Receptor: pancreas monitors blood glucose.
    • If too high: beta cells release insulin (enables cells to absorb glucose).
    • If too low: alpha cells release glucagon (liver releases glucose into blood).

Key Terms & Definitions

  • Feedback Loop — System where output is recycled as input to maintain stability.
  • Receptor — Organ that detects changes in a condition (stimulus).
  • Effector — Organ that acts to correct the change (response).
  • Stimulus — Change detected by the receptor.
  • Response — Action carried out by the effector to restore balance.
  • Negative Feedback — Counteracts change to maintain a set point.
  • Positive Feedback — Amplifies change away from a set point.

Action Items / Next Steps

  • Be able to identify receptors, effectors, stimuli, and responses in feedback loops.
  • Practice drawing and labeling feedback loop diagrams for biological processes.
  • Review textbook examples of feedback loops (e.g., thermoregulation, blood glucose).