Axial Filament in Spirochetes 3/5

Aug 16, 2025

Overview

This lecture explains the axial filament, a special type of flagella found in certain spiral-shaped bacteria, and its role in bacterial movement.

Axial Filament Structure and Function

  • The axial filament is a unique flagella type, also called an endoflagella.
  • It attaches at one end of the cell and wraps around the organism in a spiral fashion.
  • It is used for motility, enabling movement similar to a corkscrew or drill bit.

Organisms with Axial Filament

  • Axial filaments are found only in spirochete bacteria (spiral-shaped bacteria).
  • Key examples include Treponema pallidum (causes syphilis) and Borrelia burgdorferi (causes Lyme disease).

Mechanism of Movement

  • When the axial filament contracts, it causes the cell to spin or rotate.
  • This spinning action drills the bacterium forward or backward through its environment.

Key Terms & Definitions

  • Axial filament — a flagella-like structure inside spirochetes that wraps around the cell, allowing corkscrew movement.
  • Endoflagella — another name for axial filament.
  • Spirochete — a type of spiral-shaped bacterium.
  • Treponema pallidum — spirochete bacterium causing syphilis.
  • Borrelia burgdorferi — spirochete bacterium causing Lyme disease.

Action Items / Next Steps

  • Memorize the two key spirochete examples and diseases they cause.
  • Review diagrams or images of axial filaments in spirochetes for visual understanding.