Acetaminophen (Paracetamol/Tylenol) Lecture Notes

Introduction

• Acetaminophen: Also known as paracetamol and commonly referred to by the trade name Tylenol.
• Clinical Uses: Used to treat pain and reduce fever.

Memory Aids

• Cedar Mini Fan: Symbolizes acetaminophen.
  • Cedar fan = sounds like acetaminophen.

Clinical Uses

Pain Relief

• Symbol: Splinter and band-aids in the mini-fan scenario.
  • Indicates acetaminophen's analgesic (painkilling) properties.
  • Useful for minor pain control.
  • Preferred for those who cannot take NSAIDs or opioids.

Fever Reduction

• Symbol: Thermometer in the woman's mouth.
  • Indicates its antipyretic (fever-reducing) properties.

Side Effects

Hepatotoxicity (Liver Damage)

• Symbol: Liver-shaped lever in the first aid kit.
  • Highlights the risk of liver damage from acetaminophen.
  • Black box warning for hepatotoxicity.
  • Overdose risk if large amounts are taken in a short time.

Dosage Recommendations

• Safe Limit: Maximum of 4 grams per day.
  • Symbol: 4G service (4 grams per day limit).
  • Always calculate total acetaminophen intake, including in combination drugs.

Overdose Management

Antidote

• Acetylcysteine
  • Symbol: Cysteine Chapel.
  • Administered to minimize liver damage in case of overdose.

Recap

• Acetaminophen: Treats pain and reduces fever.
• Key Side Effect: Hepatotoxicity, limit to under 4 grams daily.
• Overdose Antidote: Acetylcysteine to protect the liver.

Additional Resources

• Fact lists and interactive review images available for further learning.

Remember these key points for a thorough understanding of acetaminophen and its clinical applications. Always be mindful of dose limits and the potential for liver damage.