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Eukaryotic Cell Organelles Overview

Sep 14, 2025

Overview

This lecture covers key organelles unique to eukaryotic cells, focusing on their structures, functions, and differences between plant and animal cells.

Endoplasmic Reticulum (ER)

  • The ER is a continuous network of membranes connected to the nuclear envelope.
  • Rough ER has ribosomes attached and is a site of protein synthesis and modification.
  • Smooth ER lacks ribosomes, synthesizes lipids and carbohydrates, produces some hormones, detoxifies substances, and stores calcium ions.
  • The structure of ER can shift between rough and smooth based on cell needs.

Golgi Apparatus

  • The Golgi apparatus is a stack of individual, unconnected membrane sacs.
  • Functions to sort, package, tag, and distribute proteins and lipids received from the ER.
  • Described as the "UPS" of the cell due to its role in distribution.

Vesicles and Vacuoles

  • Vesicles are small membrane sacs for transport within the cell, such as moving proteins from ER to Golgi or to the plasma membrane.
  • Vacuoles are mainly for storage; the central vacuole in plant cells stores water and maintains cell structure.

Lysosomes and Peroxisomes

  • Both are small, enzyme-filled membrane sacs for breaking down molecules.
  • Lysosomes (animal cells) contain acid hydrolases to digest old organelles and foreign material.
  • Peroxisomes (plant and animal cells) detoxify substances and break down fatty and amino acids.
  • Plant cells use vacuoles for lysosome-like functions.

Endomembrane System

  • Includes the nuclear envelope, ER, Golgi, vesicles, lysosomes, and plasma membrane.
  • Coordinates protein and lipid synthesis, modification, sorting, and distribution using interconnected membranes.

Cytoskeleton

  • Comprised of protein fibers: microtubules, microfilaments (actin filaments), and intermediate filaments.
  • Microtubules are hollow protein tubes acting as "train tracks" for organelle and vesicle movement; form spindle fibers for chromosome separation.
  • Microfilaments are thin actin strands involved in cell movement, muscle contraction, and cytokinesis.
  • Intermediate filaments provide cell shape, strength, and structural integrity; types vary by tissue.
  • The cytoskeleton maintains cell shape, enables movement, and organizes organelles.

Centrioles and Centrosomes

  • Centrioles are microtubule structures found only in animal cells, always in pairs.
  • Located in the centrosome, they organize spindle fibers for chromosome separation during cell division.

Key Terms & Definitions

  • Endoplasmic Reticulum (ER) — Network of membranes for synthesis and modification of molecules.
  • Golgi Apparatus — Stacked membrane sacs that sort and distribute cellular products.
  • Vesicle — Membrane sac for transport within cells.
  • Vacuole — Membrane sac for storage, especially prominent in plant cells.
  • Lysosome — Enzyme-filled sac in animal cells for digesting materials.
  • Peroxisome — Membrane sac with enzymes for detoxification and breakdown of fatty acids.
  • Cytoskeleton — Network of protein fibers providing shape and movement.
  • Microtubule — Hollow protein tube for intracellular transport and cell division.
  • Microfilament — Thin, actin-based strand for movement and structure.
  • Intermediate Filament — Multiple protein strands twisted for strength and structure.
  • Centriole — Microtubule-based structure in animal cells aiding cell division.
  • Centrosome — Region containing centrioles, organizing spindle fibers.

Action Items / Next Steps

  • Review diagrams of organelles, especially the ER and Golgi.
  • Watch recommended YouTube videos on cytoplasmic streaming and the endomembrane system.
  • Prepare for upcoming topics on cell wall, chloroplasts, mitochondria, endosymbiosis, flagella, cilia, fimbriae, and pili.