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Skin Cancer Overview

Jun 6, 2025

Overview

The video discusses skin cancer, its main types, risk factors, identification, and treatment options, aiming to educate viewers on early detection and management.

Introduction and Background

  • The topic was chosen in response to a viewer question during an Instagram live session.
  • Both dermatologists emphasize the importance and prevalence of skin cancer.
  • Personal experience with skin cancer is shared to highlight real-world relevance.

Main Types of Skin Cancer

  • The three most common skin cancers are basal cell carcinoma, squamous cell carcinoma, and melanoma.
  • Basal cell carcinoma is the most common and least severe, followed by squamous cell, with melanoma being the rarest and most aggressive.
  • Merkel cell carcinoma is a rare but increasingly recognized form.

Causes and Risk Factors

  • Skin cancer development is multifactorial, with sun (UVB) exposure as the major risk factor.
  • Genetics and certain viruses (e.g., HPV for squamous cell) also contribute.
  • Fair-skinned individuals are at higher risk, but anyone can develop skin cancer.

Identification and Warning Signs

  • Basal cell carcinomas often appear as pearly pimples or non-healing sores, sometimes with visible blood vessels.
  • Squamous cell carcinomas usually begin as actinic keratoses—scaly, persistent bumps on sun-exposed areas that can become thick and tender.
  • Melanomas are identified using the ABCDE rule: asymmetry, irregular borders, multiple colors, diameter >6mm, and evolving changes; the “ugly duckling” sign is also important.
  • Not all melanomas are pigmented (“amelanotic”) and can be hard to spot.

Importance of Early Detection

  • Early detection significantly improves outcomes for all skin cancer types.
  • Regular self-examinations and prompt evaluation of abnormal skin findings are encouraged.

Treatment Options

  • Treatments include surgical (excision, electrodesiccation and curettage, Mohs surgery), radiation therapy, topical agents, immunotherapy, and chemotherapy.
  • Surgical removal often requires excising additional surrounding skin to ensure clear margins, sometimes resulting in larger scars.
  • Radiation and newer targeted or immune-based treatments are used for more advanced or inoperable cases.
  • Topical treatments like fluorouracil or imiquimod are used for superficial cancers or precancerous changes.

Merkel Cell Carcinoma and Other Rare Skin Cancers

  • Merkel cell carcinoma is rare, aggressive, and often sun- and virus-related.
  • It lacks a classic appearance, making diagnosis challenging.
  • A broad array of rare skin cancers exists, though most are uncommon.

Recommendations / Advice

  • Seek medical evaluation for any new, changing, or unusual skin lesions.
  • Do not delay appointments for concerning changes, even if access is difficult.
  • Cancer diagnosis is confirmed with a biopsy, not just visual examination.

Questions / Follow-Ups

  • Consider more detailed information on surgical options like Mohs surgery in future videos.
  • Further education on rare skin cancers may be beneficial.