Lecture Notes: Testosterone Cream Dosages

Overview of Testosterone Cream Application

• Type of Cream: Compounded transcrotal cream.
• Method: Transdermal application.
• Frequency:
  • Typically: Twice a day (AM and PM).
  • For Hyper Excretors: May require three times a day.

Dosage and Application

• Common Dosage: 200 mg per day is typical.
• Strength and Measurements:
  • 10% Cream: 100 mg per gram.
  • 20% Cream: 200 mg per gram.
• Application Mechanics:
  • One click = 0.25 mL (quarter of a gram).
  • 30-gram tube = four clicks for 1 mL.

Absorption Factors

• Absorption Rate: Faster than injectables due to non-esterized nature; it is broken down quicker.
• Surface Area: The absorption rate for higher concentration creams (e.g., 20%) is not as efficient due to reduced surface area coverage.
  • Example: Using 200 mg cream may not directly equate to half the clicks of a 100 mg cream because of smaller surface area used.

Typical Usage Patterns

• Average Application:
  • Two clicks in the morning.
  • Two clicks at night.
• Adjustments:
  • Adjust up or down based on individual response and symptom resolution.
  • Some individuals (e.g., those with muscular build) may require higher dosages (e.g., 300 mg per day).

Personalization of Dosage

• Individual Variability:
  • Symptom resolution varies; some may experience side effects at common dosages.
  • Dosage may need to be personalized based on physical characteristics and personal response to the cream.

Key Takeaways

• Common Dosage: 200 mg per day is widely effective for most users.
• Customization: Dosage can be tailored based on individual needs and physical responses.
• Goal: Achieve symptom resolution effectively.