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Prokaryotic vs. Eukaryotic Cells

Sep 5, 2025

Overview

This lecture explains the key structural differences between prokaryotic and eukaryotic cells, focusing on prokaryotic cell components relevant for A-Level Biology.

Prokaryotic vs. Eukaryotic Cells

  • Prokaryotic cells are much smaller than eukaryotic cells.
  • Prokaryotic cells do not have membrane-bound organelles.
  • Eukaryotic cells contain organelles like mitochondria, chloroplasts, endoplasmic reticulum, Golgi apparatus, and a nucleus.
  • Prokaryotes have ribosomes, but these are smaller (70S) compared to eukaryotic ribosomes (80S).
  • Eukaryotic mitochondria and chloroplasts have some 70S ribosomes for their own protein synthesis.
  • Prokaryotes do not have a nucleus; their DNA is circular and free in the cytoplasm.
  • Eukaryotic cells have a nucleus with linear chromosomes and histone proteins.

Prokaryotic Cell Structures

  • The cell wall in prokaryotes is made of murine, a glycoprotein.
  • Plant eukaryotic cell walls are made of cellulose; fungi have chitin in their walls.
  • Some prokaryotes have plasmids, which are small loops of extra DNA carrying a few genes (often antibiotic resistance).
  • Some have a capsule, a slimy protein layer outside the cell wall, protecting against desiccation and immune system detection.
  • Some prokaryotes have flagella (singular: flagellum), tail-like structures that rotate to enable movement.

Key Terms & Definitions

  • Prokaryotic cell — A cell lacking membrane-bound organelles and a nucleus; example: bacteria.
  • Eukaryotic cell — A cell with membrane-bound organelles and a nucleus; examples: plants, animals, fungi.
  • 70S ribosome — Smaller ribosome type found in prokaryotes, mitochondria, and chloroplasts.
  • 80S ribosome — Larger ribosome type found in eukaryotic cells.
  • Plasmid — Small loop of DNA in prokaryotes, often carrying antibiotic resistance genes.
  • Capsule — Protein layer outside some prokaryotic cells for protection.
  • Flagellum/Flagella — Tail-like structure(s) enabling movement in some prokaryotes.
  • Murine — Glycoprotein making up prokaryotic cell walls.

Action Items / Next Steps

  • Review and memorize the differences between prokaryotic and eukaryotic cells.
  • Learn the functions and structures unique to prokaryotic cells for exam questions.