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Key Tips for AP Biology Exam Prep

May 2, 2025

AP Biology Last Minute Cram Session

General Tips for AP Biology Exam

  • Test Format: 3 hours, split into two 90-minute parts:
    • Part 1: 60 multiple choice questions
    • Part 2: 6 free-response questions (FRQs)
  • Weighting: Both sections are weighted equally (50% each)
    • 2 long and 4 short FRQs
  • Preparation Tips:
    • Bring: 2 pens (blue/black), 2 pencils (#2), a calculator (non-internet)
    • Provided: Formula sheet, extra paper
    • IDs required if testing at a non-home school location
    • No electronic devices (phones, smartwatches, etc.)

Multiple Choice Tips

  • Answer all questions; no penalty for wrong answers
  • Skim questions first, then read stems/stimuli
  • Allocate ~1 minute per question

Free Response Tips

  • Answer in complete sentences; avoid bullet points unless specified
  • Focus on clarity over grammar perfection
  • Spend more time on long FRQs; they are worth more points
  • Be specific in calculations and rounding as instructed

Key Content Topics

Cell Biology

  • Basic Unit of Life:
    • Cell membrane: phospholipid bilayer
    • Cytoplasm and genetic material (DNA)
  • Signal Transduction Pathways: Signal → Transduction → Response
    • Can lead to gene expression, hormone production, or apoptosis

Molecular Biology

  • Protein Synthesis:
    • DNA → mRNA (transcription in nucleus)
    • mRNA → Protein (translation in cytoplasm)
  • Gene Regulation:
    • Prokaryotic: Operons (e.g., Lac operon)
    • Eukaryotic: Introns removed, exons spliced in mRNA processing
  • Biotechnology:
    • PCR, gel electrophoresis, DNA sequencing

Macromolecules

  • Types:
    • Nucleic acids (nucleotides)
    • Proteins (amino acids)
    • Carbohydrates (monosaccharides)
    • Lipids (fatty acids, glycerol)

Energetics

  • Cellular Respiration:
    • Glycolysis (cytosol), Krebs cycle (mitochondrial matrix), Oxidative phosphorylation (inner mitochondrial membrane)
    • Oxygen as the final electron acceptor
  • Photosynthesis:
    • Light-dependent reactions: Occur in thylakoid membranes
    • Calvin Cycle: Occurs in stroma, fixes CO2 into sugars

Ecology and Evolution

  • Feedback Mechanisms:
    • Negative: Maintain homeostasis (e.g., temperature, blood sugar)
    • Positive: Amplifies change (e.g., childbirth contractions)
  • Evolution:
    • Natural selection, genetic drift, gene flow
    • Evidence from morphology, molecular data

Genetics

  • Inheritance Patterns:
    • Mendelian (single gene), dihybrid, sex-linked
    • Mitochondrial inheritance (maternal line)

Populations and Ecology

  • Population Dynamics:
    • Effect of environmental pressures on natural selection
    • Role of biodiversity in ecosystem resilience

Scientific Skills

  • Experimentation:
    • Dependent vs. independent variables
    • Null hypothesis for statistical tests
  • Graphing and Data Analysis:
    • Use line/bar graphs appropriately
    • Interpret error bars and significance

Math & Formulas

  • Familiar with Chi-square, Hardy-Weinberg, water potential
  • Understand statistical significance and degrees of freedom

Final Advice

  • Review topics thoroughly
  • Practice with past papers
  • Utilize resources for full understanding

Additional Resources

  • The presenter has additional AP Biology resources on their channel for further study and preparation.