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Skin Glands Overview

Jun 9, 2025

Overview

This lecture reviews the three main types of skin glands—holocrine, apocrine, and merocrine—focusing on their structure, secretion methods, locations, and functions.

Types of Skin Glands

  • There are three types of glands in the skin: holocrine, apocrine, and merocrine glands.
  • All glands are located in the reticular dermis and have ducts that lead to the skin surface.

Holocrine (Sebaceous) Glands

  • Holocrine glands release their secretion by disintegrating the whole cell.
  • Their secretion is called sebum, an oily, lipid-rich substance.
  • Holocrine (sebaceous) glands are found on the face, chest, and back.
  • Sebum lubricates the skin and slows bacterial growth.

Apocrine Glands

  • Apocrine glands release a mix of proteins, lipids, and steroids by shedding the cell apex.
  • Mainly located in the armpits, groin, and around the nipples.
  • Apocrine glands release contents into hair follicles, unlike the other types.
  • They become active after puberty and are involved in emotional sweating (anxiety, stress, fear, pain).

Merocrine (Eccrine) Glands

  • Merocrine glands secrete watery, salty sweat via exocytosis.
  • Found throughout the body, especially on palms and soles.
  • Functions include evaporative cooling, waste elimination, and microbial defense.
  • Merocrine sweat contains lysozymes (break down bacteria) and antibodies (tag pathogens).

Key Terms & Definitions

  • Holocrine gland — gland that releases its secretion by destroying the whole cell.
  • Sebum — oily secretion of holocrine (sebaceous) glands.
  • Apocrine gland — gland that releases secretions by breaking off part of the cell apex.
  • Merocrine (eccrine) gland — gland that secretes sweat by exocytosis.
  • Lysozyme — enzyme in sweat that destroys bacteria.
  • Antibody — immune protein in sweat that identifies foreign invaders.

Action Items / Next Steps

  • Review differences in secretion methods and locations of each gland type.
  • Prepare for questions on gland functions and significance in skin physiology.