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Introduction to Genetics Concepts

Aug 23, 2024

Basics of Genetics Lecture Notes

Definition of Genetics

  • Genetics: A branch of biology concerned with the study of genes, genetic variation, and heredity in organisms.
  • Focuses on the study of genes and how they vary and are inherited.

Understanding Traits

  • Trait: A physical characteristic or attribute of an organism, e.g., height, eye color, skin color, hair color.
    • Example: A girl with black hair, brown skin, and short height has these traits.

Cells and DNA

  • Cell: The smallest structural and functional unit of an organism.
  • Nucleus: Contains the chromosomes.
  • Chromosome: DNA wrapped around proteins, condensed to fit within the nucleus.
    • DNA is a long double helical structure that must condense to fit in the nucleus.

DNA and Chromosomes

  • DNA: A long, double-helical structure.
  • Chromosome: Formed when DNA is coiled and condensed around proteins.
  • Chromosomes allow DNA to fit into the small nucleus.

Genes

  • Gene: A segment of DNA that codes for specific proteins that express traits.
    • Not all DNA is coding; only certain segments are involved in protein coding.
    • Allele: One gene in a pair (homologous chromosomes) that codes for a specific trait.

Homologous Chromosomes

  • Homologous Chromosomes: Similar in size and structure, carrying genes for the same traits.
  • Example: Genes coding for height are present on homologous chromosomes.

Key Concepts

  • Locus: The specific location of a gene on a chromosome.
  • Heterozygous: An organism with one dominant allele and one recessive allele, e.g., Tt (where T is dominant for tall).
  • Homozygous: An organism with two identical alleles.
    • Homozygous Dominant: Two dominant alleles (e.g., TT) results in a tall phenotype.
    • Homozygous Recessive: Two recessive alleles (e.g., tt) results in a short phenotype.

Phenotype and Genotype

  • Genotype: The genetic makeup of an organism, indicating which genes are present.
    • Example: TT, Tt, or tt for height.
  • Phenotype: The physical appearance of an organism, determined by genotype.
    • Example: Tall (Tt, TT) or short (tt) plants.

Summary

  • This lecture covered the basics of genetics including definitions of key terms such as genes, traits, alleles, homologous chromosomes, locus, heterozygous, homozygous, genotype, and phenotype.
  • Understanding these concepts is crucial for studying inheritance and variation in organisms.