Understanding Body Fluid Compartments and Osmosis

Oct 5, 2024

Lecture on Body Fluid Compartments and Osmosis

Overview

  • The average adult body consists of 60-70% water.
  • Body fluids are stored in two main compartments:
    • Intracellular compartment: Fluid within the cell.
    • Extracellular compartment: Fluid outside the cell, includes intravascular fluid, interstitial fluid, and transcellular fluid.

Intracellular Space

  • Accounts for two-thirds of body water.
  • Fluid is found inside the cells.

Extracellular Space

  • Accounts for one-third of body water.
  • Comprises:
    • Intravascular fluid compartment (plasma): Fluid inside blood vessels, contains electrolytes, blood cells, etc.
    • Interstitial fluid compartment: Fluid surrounding the outside of cells, crucial for transporting substances to and from cells using capillaries.
    • Transcellular fluid compartment: Smallest compartment, includes fluids in body cavities like spinal fluid, fluids around heart and lungs, and joints.

Importance of Fluid Compartments

  • All compartments are interconnected, maintaining homeostasis by shifting water, electrolytes, and nutrients.
  • Shifting is done through processes like osmosis, crucial for correcting fluid imbalances.

Osmosis

  • Definition: Movement of water from higher concentration to lower concentration of water, or from a fluid with low solute concentration to high solute concentration.
  • Occurs passively through a semi-permeable membrane, only permeable to water.

Key Points on Osmosis

  • Highly influenced by fluid solute concentration.
  • Solutes: Solids dissolved in liquid, e.g. sodium and chloride, which are electrolytes when dissolved.

Osmolarity

  • Definition: Amount of solutes per liter of solution.
  • Determines how osmosis affects fluid shift between extracellular and intracellular compartments.
  • High osmolarity: High solute concentration, less water.
  • Low osmolarity: Low solute concentration, more water.

Application in Healthcare

  • Osmolarity is used to treat patients by administering fluids with varying osmolarities to shift water in or out of compartments based on needs.

  • Further information or continuation of this series can be accessed via the provided YouTube link.