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Introduction to the Mole in Chemistry

Sep 6, 2025

Overview

This lecture introduces the concept of the mole in chemistry, explaining its definition, significance, and various ways to calculate moles for quantitative problem-solving in chemical reactions.

What is a Mole?

  • A mole is the SI unit for the amount of substance in chemistry.
  • One mole equals 6.022 × 10²³ particles (atoms, molecules, or ions).
  • 6.022 × 10²³ is called Avogadro’s number or Avogadro’s constant.
  • Chemists use moles because counting individual atoms is impractical.
  • The mole is analogous to using "dozen" for 12; "one mole" means 6.022 × 10²³ particles.
  • The definition: one mole is the amount of substance containing as many particles as 12 grams of carbon-12 atoms.

Properties of the Mole

  • One mole of any substance contains 6.022 × 10²³ representative particles, regardless of identity.
  • Avogadro’s number is always used to relate moles to number of particles.
  • The mole concept enables chemists to relate masses of substances to numbers of particles for calculations.

Calculating Moles

  • Use ( n = \frac{m}{M} ) if given mass (m) and molar mass (M).
  • Use ( n = c \times V ) if given concentration (c) and volume (V) of solution.
  • Use ( n = \frac{V}{V_m} ) for gases at standard temperature and pressure (STP), where ( V_m = 22.4 ) dm³.
  • Use ( n = \frac{N}{N_A} ) if given number of particles (N); ( N_A ) is Avogadro’s number.
  • "n" represents the number of moles in all formulas.

Why Use Moles in Chemical Reactions?

  • Chemists use moles to calculate amounts of reactants and products in reactions.
  • Balanced chemical equations indicate moles of reactants/products using coefficients.
  • To convert mass of a substance to moles, then use mole ratios to relate substances.
  • Mole ratios help determine how much product forms or reactant is needed.

Key Terms & Definitions

  • Mole (mol) — SI unit for amount of substance; equals 6.022 × 10²³ particles.
  • Avogadro’s number (N_A) — 6.022 × 10²³, the number of particles per mole.
  • Molar mass (M) — Mass in grams of one mole of substance.
  • Concentration (c) — Amount of solute per volume of solution, in mol/dm³.
  • STP — Standard Temperature and Pressure, conditions used for gas volume calculations.
  • Mole Ratio — The ratio of moles of reactants/products from a balanced equation.

Action Items / Next Steps

  • Review the formulas for calculating moles based on different information given.
  • Watch videos on stoichiometry, mole calculations, and mole ratios for detailed examples.
  • Practice converting between mass and moles, and using mole ratios in balanced equations.