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Medical Prefixes Overview

Sep 9, 2025

Overview

This lecture introduces common medical prefixes, providing meanings and example terms to help decipher medical vocabulary.

Prefixes Meaning "Without"

  • "A-" and "an-" prefixes mean "without" (e.g., apnea = without breath; achlorhydria = without stomach acid).
  • Apnea refers to not breathing; achlorhydria is too little stomach acid; atony is loss of muscle tone.
  • Anaerobic means without oxygen (e.g., anaerobic metabolism).
  • Anemia means without or lacking blood (technically low hemoglobin).
  • Anesthesia means without sensation.

Prefixes Meaning "Against" or "Before"

  • "Anti-" means against (e.g., antibiotic = against bacteria; anti-inflammatory = against inflammation).
  • "Ant(e)-" means before (e.g., antenatal = before birth).

Prefixes Indicating Speed

  • "Brady-" means slow (e.g., bradypnea = slow breathing; bradycardia = slow heart rate).
  • "Tachy-" means abnormally fast (e.g., tachycardia = fast heart rate; tachypnea = fast breathing).

Heart and Blood Prefixes

  • "Cardi/o-" refers to the heart (e.g., cardiologist = heart specialist; cardiomegaly = enlarged heart).
  • "Hem-/haem-" refers to blood (e.g., hematuria = blood in urine; hematology = study of blood).
  • "Hemi-" means half (e.g., hemiplegia = paralysis of half the body).

Gastrointestinal and Biliary Prefixes

  • "Col-/coli-" relates to the colon (e.g., colitis = colon inflammation; colostomy = surgical colon opening).
  • "Chol-/chole-" refers to bile (e.g., cholecystectomy = gallbladder removal; cholangitis = bile duct inflammation).
  • "Cyst-" means bladder or fluid-filled sac (e.g., cystitis = bladder inflammation).
  • "Gastr/o-" refers to the stomach (e.g., gastritis = stomach inflammation).

Other Common Prefixes

  • "Endo-" means inside (e.g., endoscopy = looking inside; endocardium = inner heart layer).
  • "Enter/o-" means intestine (e.g., enteritis = intestine inflammation).
  • "Dys-" means abnormal or painful (e.g., dysuria = painful urination; dysphagia = difficulty swallowing).
  • "Glyc-" refers to sugar (e.g., hypoglycemia = low blood sugar; glycogen = stored sugar).
  • "Lipo-" refers to fat (e.g., lipoma = benign fatty lump; dyslipidemia = abnormal blood fats).
  • "Mal-" means abnormal (e.g., malnutrition = poor nutrition; malabsorption = poor absorption).
  • "Mast-" refers to breast (e.g., mastectomy = breast removal; mastitis = breast inflammation).
  • "Myo-" refers to muscle (e.g., myocardium = heart muscle; myopathy = muscle disease).
  • "Nephr/o-" refers to kidney (e.g., nephritis = kidney inflammation; nephrologist = kidney specialist).
  • "Pyo-" means pus (e.g., pyelonephritis = infection of kidney and pelvis).
  • "Hydr/o-" means water or sometimes urine (e.g., hydronephrosis = urine accumulation in kidney).
  • "Oligo-" means few or scanty (e.g., oliguria = low urine output).

Key Terms & Definitions

  • Prefix — a word part added at the beginning of a term to modify its meaning.
  • Anemia — low hemoglobin or red blood cell levels.
  • Antibiotic — substance that kills bacteria.
  • Bradycardia — slow heart rate.
  • Cardiomegaly — enlarged heart.
  • Cholecystectomy — surgical removal of the gallbladder.
  • Colitis — inflammation of the colon.
  • Dysuria — painful urination.
  • Hypoglycemia — low blood sugar.
  • Lipoma — benign fat tumor.
  • Mastectomy — surgical breast removal.
  • Nephritis — kidney inflammation.
  • Tachypnea — rapid breathing.

Action Items / Next Steps

  • Review and memorize common prefixes and their meanings.
  • Practice breaking down complex medical terms using prefixes and suffixes.
  • Prepare a list of unfamiliar prefixes for further clarification.