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Liver Ultrasound Anatomy Overview

Jul 20, 2025

Overview

This lecture covers the normal ultrasound anatomy of the liver, including grayscale characteristics, vascular supply, anatomical segmentation, and key measurements.

Liver Lobes and Segments

  • The liver is divided into right, left, and caudate lobes.
  • The main lobar fissure, passing through the gallbladder fossa, separates the right and left lobes.
  • The right lobe divides into anterior and posterior segments.
  • The left intersegmental fissure divides the left lobe into medial and lateral segments.
  • The caudate lobe is posterior, bordered by the inferior vena cava (IVC) and ligamentum venosum fissure.
  • Reidel’s lobe is a tongue-like extension of the right lobe's inferior tip, often seen in thin women.

Vascular Anatomy of the Liver

  • There are three hepatic veins: right, middle, and left.
  • The right hepatic vein divides the right lobe into anterior and posterior segments.
  • The middle hepatic vein separates the right lobe's anterior segment from the left lobe's medial segment.
  • The left hepatic vein divides the left lobe into medial and lateral segments.
  • Hepatic veins are intersegmental/interlobar (run between segments/lobes), while portal veins are intrasegmental (within segments).
  • The portal vein forms from the union of intestine, spleen, pancreas, and gallbladder veins and splits into right and left branches at the porta hepatis.
  • Portal veins are seen as bright echogenic-walled structures on ultrasound; hepatic veins lack echogenic borders.

Key Anatomic Landmarks

  • The ligamentum venosum fissure is the anterior border of the caudate lobe; IVC is the posterior border.
  • The ligamentum teres separates medial and lateral left lobe segments and appears as an echogenic structure.

Segmental (Couinaud) Anatomy

  • The liver contains 8 segments, each with its own vascular and biliary supply.
  • Segments are determined by hepatic and portal vein branches.
  • Segment 1 (caudate lobe) may receive blood from both portal vein branches and drains directly to the IVC.

Grayscale Echogenicity

  • Liver is homogeneous with fine, low-level echoes.
  • Liver is hypoechoic or isoechoic to the pancreas, hyperechoic or isoechoic to the right kidney, and always hypoechoic to the spleen.
  • Left lobe enlargement wrapping around the spleen is called "beaver tail" and may mimic hematoma but can be distinguished by vessel visualization and Doppler.

Liver Size Measurements

  • Liver length is measured at the mid-clavicular line.
  • Normal average liver length: 14 ± 1.7 cm; men average: 14.5 ± 1.7 cm, women: 13.5 ± 1.7 cm.
  • Liver length ≥16 cm at mid-clavicular line is considered enlarged.

Key Terms & Definitions

  • Hyperechoic — produces more echoes; appears brighter on ultrasound.
  • Hypoechoic — produces fewer echoes; appears darker on ultrasound.
  • Isoechoic — similar in echogenicity to surrounding tissue.
  • Intersegmental — between liver segments (e.g., hepatic veins).
  • Intrasegmental — within a liver segment (e.g., portal veins).
  • Couinaud Anatomy — universal liver segmentation system based on portal and hepatic vein anatomy.

Action Items / Next Steps

  • Review the segmental anatomy and Couinaud classification.
  • Practice identifying portal and hepatic veins and liver landmarks on ultrasound images.
  • Memorize normal liver size thresholds for exams.