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AP Biology Exam Strategies and Topics

May 5, 2025

AP Biology Exam Review

Overview

  • Final review video by Mr. Anderson for the AP Biology exam.
  • Answers top 20 questions received from students globally.
  • Provides exam setup and strategies.
  • Includes shoutouts to students worldwide.

Exam Setup & Strategy

  • Two parts: Multiple choice and Free response.

Multiple Choice

  • Duration: 90 minutes.
  • Includes: 63 multiple choice questions, 6 grid-in questions.
  • Use of calculator allowed.
  • Strategy:
    • Spend about 1 minute per question.
    • Use process of elimination.
    • No penalty for guessing.
    • Last year needed 79% for a score of 5.

Free Response

  • Two long questions and six short questions.
  • Total: 80 minutes.
  • Strategy:
    • Plan during the 10-minute reading period.
    • Follow descriptive words in questions (Explain, Justify).
    • Give specific evidence when asked.

Key Topics

Hardy-Weinberg Equilibrium

  • Large population, random mating, no mutations, no gene flow, no selection.
  • Allele frequencies remain constant.
  • Equation: p^2 + 2pq + q^2 = 1.

Chi-squared Test

  • Used in genetics and animal behavior.
  • Observed vs. expected values.
  • Degrees of freedom = number of categories - 1.
  • Use critical values from Chi-squared table.

Cellular Respiration

  • Glycolysis: Breakdown of glucose (6C) into pyruvate (3C).
  • Krebs Cycle: Release of CO2, energy carriers (NADH, FADH2).
  • Electron Transport Chain: Proton gradient creation, ATP synthesis.

Photosynthesis

  • Light Reactions: Occur in thylakoid membrane, ATP synthesis.
  • Calvin Cycle: Occurs in stroma, sugar production.
  • Water's role in donating electrons.

DNA & RNA

  • DNA Structure: Nucleotide composition, 5’ to 3’ direction.
  • RNA vs. DNA: Sugar type, single/double strand.
  • Transcription: RNA polymerase, mRNA formation.
  • Translation: mRNA codons, tRNA anticodons, protein synthesis.

Cell Cycle

  • G1: Cell growth.
  • S: DNA replication.
  • G2: Preparation for mitosis.
  • M: Mitosis (cell division), Meiosis (gamete formation).

Enzymes

  • Protein structure, substrate interaction.
  • Active site, induced fit mechanism.

Immune System

  • Macrophages, antigen presentation, helper T cells.
  • Humoral response: B cells, antibodies.
  • Cell-mediated response: Killer T cells.

Cell Communication

  • Signal transduction pathways.
  • Types: Direct contact, neurotransmission, endocrine signaling.

Feedback Loops

  • Negative feedback: Glucose regulation (insulin/glucagon).
  • Type 1 and Type 2 diabetes explanation.

Phylogenetics

  • Reading phylogenetic trees: Common ancestors, speciation.
  • Evidence: Morphological and molecular (DNA/RNA).

Conclusion

  • Encouragement and good luck wishes.
  • Shoutouts to students and classes worldwide.
  • Reminder to enjoy the summer ahead.