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Enhancing Medication Safety in Anesthesia

May 10, 2025

Lecture on Medication Safety and Error Prevention

Introduction

  • Incident Overview: A healthy child scheduled for elective ear surgery died due to a medication error involving epinephrine.
    • Incorrect concentration of epinephrine (1:1000) was injected instead of the intended anesthetic.
    • The situation led to a sense of dread and panic among healthcare providers.

Medication Errors

  • Definition: Medication errors are preventable events leading to inappropriate medication use or harm.
  • Sources:
    • Errors often occur during medication administration in hospital settings.
    • Particular concern for anesthesia professionals with sparse data but frequent errors.

Statistics and Data

  • ASA Closed Claims Database:
    • Medication errors account for 4% of cases.
    • Types of errors: substitution errors, insertion errors, incorrect dosing.
    • Significant adverse effects occurred in nearly 50% of claims.

Causes of Medication Errors

  • Lack of standardization and protocols.
  • Production pressures and absence of checks and balances in operating rooms (OR).
  • Common errors include syringe swaps, wrong drug selection, and labeling errors.
  • Contributing factors: haste, inattention, communication failure, and fatigue.

Recommendations and Strategies

  • Safe Practices:
    • Emphasize standardized labeling, proper syringe labeling, and color coding.
    • Address system changes rather than relying on flawless human performance.

STPC Paradigm

  • Standardization: Focus on drug dosages, concentrations, and preparation methods.
  • Technology: Use of barcoding, computer-assisted delivery, and error interception systems.
  • Pharmacy: Encourage pre-mixed solutions and pre-filled syringes, with clinical pharmacists involved in the OR.
  • Culture: Establish a non-punitive culture for error reporting and learning from adverse events.

Implementation in Practice

  • Wake Forest University Baptist Medical Center Example:
    • Standardized drug infusions and syringes prepared by pharmacy.
    • Use of smart infusion pumps with standardized drug libraries.
    • Mandatory training for all staff on new practices.

Conclusion

  • Adoption of the STPC Paradigm is encouraged to enhance medication safety.
  • Anesthesia professionals and hospitals should collaborate for successful implementation.
  • Improvement in medication delivery safety and clinician satisfaction is anticipated.

Additional Resources

  • Educational materials and videos available on the APSF website.