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Carl Woese and Archaea Classification

Feb 9, 2025

Lecture Notes: Carl Woese and the Classification of Archaea

Introduction

  • Carl Woese significantly impacted biological classification.
  • He introduced the concept of a third domain: Archaea.
  • Previously, organisms were classified as either Bacteria or Eukaryotes.

Differences Between Bacteria and Archaea

General Characteristics

  • Both are single-celled organisms.
  • Neither have a nucleus nor membrane-bound organelles.
  • Both reproduce asexually.

Key Differences

  1. Cell Walls

    • Bacteria: Contain peptidylglycine.
    • Archaea: Lack peptidylglycine in their cell walls.
  2. Cell Membranes

    • Bacteria: Use fatty acid chains.
    • Archaea: Utilize isoprene chains.
  3. Genetic Code Reading Enzymes

    • Archaea have unique enzymes differing from bacterial ones.

Habitat and Impact

  • Archaea often inhabit extreme environments (e.g., hydrothermal vents, hot springs).
  • Can also be found alongside bacteria in environments like the human gut.
  • To date, no known archaea cause diseases in humans, unlike certain bacteria.

Modern Classification

  • Due to these differences, a third domain "Archaea" was proposed and accepted.
  • Current classification now includes three domains: Bacteria, Archaea, and Eukarya.

Conclusion

  • The work of Carl Woese fundamentally changed our understanding of life's classification.
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  • Note: These notes summarize the important points from the lecture on Carl Woese's contribution to biological classification and the distinctions between bacteria and archaea.