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A Level Biology Exam Guidance

Jun 2, 2025

A Level Biology A Paper D June 2021 Notes

Instructions and Information

  • Use black ink, HB pencil allowed for graphs and diagrams.
  • Write answers in the space provided, use lined pages at the end for extra space.
  • Answer all questions; marks awarded for correct methods.
  • Total marks: 100.
  • Quality of extended response assessed in questions marked with an asterisk (*).
  • Required: Insert (inside document), ruler, scientific/graphical calculator.
  • Time allowed: 2 hours 15 minutes.*

Section A

  • Focus: Multiple choice questions, time suggested: 20 minutes.

Key Questions

  1. Liver Function

    • Not a function: C (storage of excess amino acids as protein)
  2. Control of Blood Glucose

    • Correct statement: B (Glucagon stimulates conversion of glycogen to glucose)
  3. **Protein Export Path

    • Correct path: C (Rough ER โ†’ Golgi apparatus โ†’ Secretory vesicle)
  4. Enzyme Catalyzed Reactions

    • True statement: A (Binding of a substrate to the active site can weaken bonds)
  5. End-Product Inhibition

    • Example: B (Isoleucine inhibits E7)
  6. Cell Specializations

    • Correct description: B (biconcave shape, no nucleus for erythrocytes)
  7. Action Potential Events

    • Correct description: D (Position 4, no Na+ channels open, no K+ channels open)
  8. Action Potential Graph Interpretations

    • Correct statement: C (Hyperpolarization at 5, repolarization at 6)
  9. Pregnancy Test Interpretation

    • True statement: B (Strip 2, hCG binds to mobile antibodies captured by fixed at Results line)
  10. Neuron Structure Identification

    • Correct identification: A (axon, dendron, sensory neuron)
  11. Nervous Transmission

    • Incorrect statement: D (Nodes of Ranvier act as insulators)
  12. Nervous System Statements

    • Correct: B (1 and 2 are correct)
  13. Coenzymes in Cellular Respiration

    • Correct: B (NAD and FAD are coenzymes, NAD is reduced)
  14. Respirometer Investigation

    • Incorrect statement: A (Level in left-hand arm decreases)
  15. Water Transport in Plants

    • Incorrect: B (Water does not pass through Casparian strip)**

Section B

  • Focus: Short answer questions requiring written responses.

Heart and Brain Questions

  • Identify structures and describe effects of injuries to brain regions.
  • Understand the control of heart rate by the nervous system.

Pancreas and Insulin Secretion

  • Identify structures in pancreas micrograph.
  • Effect of nifedipine on insulin secretion, calcium channel block explanation.

Liver and Enzymes

  • Identify liver structures, describe enzyme adaptations.
  • Understanding of coenzymes and inhibition in enzyme activity.

Photosynthesis and Terrariums

  • Hill reaction: role of DCPIP and electron transport.
  • Adaptations for plant growth in terrariums, reasons why cacti may not thrive.

Transpiration and Xylem

  • Potometer usage and effects of air movement on transpiration rates.
  • Calculate standard deviation, and factors affecting leaf area estimation.
  • Description of xylem cell production.

Tissue Fluid and Ultrafiltration

  • Effect of solute concentrations on water potential and oncotic pressure.
  • Calculation of net driving force, implications of kidney disease on fluid dynamics.
  • Comparison between lymph and tissue fluid composition.

Notes

  • Always read questions carefully and base answers on evidence provided.
  • Consider practical applications and implications of theoretical knowledge in experiments and real-world scenarios.