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ACLS Medications for Emergency Nursing

May 7, 2025

Emergency Chaos: Key ACLS Medications Lecture

Introduction

  • Focus on improving ER nurse skills through ACLS medication knowledge.
  • Encouragement to read further on ER essentials like vasopressors and emergency conditions.

Medications Covered

  1. Epinephrine

    • Uses: Cardiac arrest, post-cardiac arrest, symptomatic bradycardia.
    • Action: Alpha, Beta-1, Beta-2 agonist increases heart rate, contraction strength, BP, and airway dilation.
    • Dosage:
      • Cardiac Arrest: 1 mg every 3-5 min (IV/IO).
      • Post-cardiac arrest infusion: 0.1 to 1 mcg/kg/min, max 2 mcg/kg/min.
      • Symptomatic Bradycardia: Infusion 2-10 mcg/min.
    • Notes: Epinephrine isn't the only vasopressor option; norepinephrine may be used.
  2. Amiodarone

    • Uses: Cardiac arrest with VFib or pulseless VTach.
    • Action: Antiarrhythmic; prolongs action potential and refractory period.
    • Dosage:
      • Initial: 300 mg IV/IO, second dose: 150 mg.
      • VTach with pulse: 150 mg over 10 min; followed by 1 mg/min for 6 hrs, then 0.5 mg/min for 18 hrs.
    • Monitoring: Side effects include bradycardia, hypotension, QT elongation.
  3. Atropine

    • Uses: Symptomatic bradycardia.
    • Action: Blocks parasympathetic stimulation, increases heart rate.
    • Dosage: 1 mg every 3-5 min, up to 3 mg max.
    • Notes: Ineffective in 3rd degree blocks; caution in ACS patients.
  4. Sodium Bicarbonate

    • Uses: Metabolic acidosis during prolonged cardiac arrest, hyperkalemia, TCA overdose.
    • Dosage: 50 mEq or 50 mL during cardiac arrest.
    • Priority: Focus on CPR, oxygenation, epinephrine, defibrillation first.
  5. Lidocaine

    • Uses: VFib, pulseless VTach.
    • Action: Sodium channel blocker, stabilizes cardiac membranes.
    • Dosage: 1-1.5 mg/kg, repeat dose 0.5-0.75 mg/kg.
  6. Magnesium

    • Uses: Polymorphic VTach (Torsades de Pointes).
    • Dosage: 2 g IV.
    • Notes: Monitor magnesium levels, watch for hypotension, bradycardia.
  7. Calcium Chloride

    • Uses: Hyperkalemia, calcium channel blocker overdose.
    • Dosage: 1 g when addressing H's & T's in cardiac arrest.
    • Note: Differentiate from calcium gluconate.
  8. Dextrose

    • Uses: Hypoglycemia, reversible cardiac arrest cause.
    • Dosage: 25 g in 50 mL if hypoglycemia detected.
  9. Adenosine

    • Uses: SVT.
    • Action: Interrupts AV node conduction.
    • Dosage: 6 mg initial dose, followed by 12 mg if needed.
    • Procedure: Administer via large bore IV with rapid saline flush.

Nursing Tips

  • Memorize ACLS medications and treatments.
  • Practice quizzing with peers or preceptors.
  • Emphasize teamwork and preparedness in emergency scenarios.

  • Conclusion: Understanding ACLS is vital for effective ER nursing; proactive team collaboration is key.