Transcript for:
Leukotriene Inhibitors Overview

lucatrine inhibitors so mechanism of action so first of all leukotriene inhibitors these are receptor antagonists okay so you want to remember way back way back when what's the difference between an agonist and an antagonist okay so lucatrine inhibitors these are receptor antagonists this begins in chapter 37 mechanism of action so we want to think about the normal function of leukotrienes first okay so when leukotrine is released so remember this is an inflammatory mediator so mediators of inflammation we have bronchoconstriction and mucus production so therefore our patient might be coughing have wheezing be short of breath um inhibitors so if we have a leukotriene inhibitor it's going to basically block that immune response right block the immune system response block those leukotrienes and the effects are really limited to just the lungs so by that important to remember are the therapeutic effects okay it prevents smooth muscle contraction okay so therefore we have decreased inflammation decreased bronchoconstriction and decreased mucus production okay important to remember for your leukotriene inhibitors indications why would we give it right so we would give this to a person for control with maybe chronic asthma and even seasonal allergies so this uh would be for prophylaxis this would be long-term treatment and prevention of asthma but they're gonna see it's gonna be at least one week to see any type of improvement okay on this type of drug so again this is not a short acting this would be a long-acting prophylaxis long-term treatment precautions precautions would be liver dysfunction because that's what's primarily metabolized contraindications would be liver failure again for the same reason side effects we have headache dizziness insomnia gi upset nausea nursing actions nursing actions as we what we want to think about here okay so we obviously with all of our other drugs the same way we're going to monitor for therapeutic effects side effects liver function um but important that we are educating our patient important to remember okay so patient education is dosing and controller we need to educate the patient to take their medication every day on a continuous schedule even if symptoms improve okay that's important well if they're not taking it every day their symptoms are just going to come back and become worse right and we kind of lose the prophylactic effect so remember this is long-term acting it takes a week before they even see any improvement so they have to take it consistently same time every day just taking on a continuous schedule even if they feel better examples of rug in class so you only have one prototype to remember here this is monte lucas montelucas is great because it has little adverse reactions okay and that's something you want to remember about that particular drug