Metacosis Perfectionatus: Genetics Lecture

Overview

• Continuation of the genetics section in the biology playlist.
• Discusses Gregor Mendel's laws of genetics:
  • First Law of Segregation
  • Second Law of Independent Assortment

Key Concepts from Previous Video

• Penetrance vs. Expressivity:
  • Expressivity:
    • Can be constant (same for everyone) or variable (varies among individuals).
    • Neurofibromatosis as an example (affects nervous system and skin).

Mendel's Laws of Genetics

First Law: Law of Segregation

• Each gene may have alternative forms (alleles).
• One allele is inherited from each parent (mom and dad).
• During meiosis, alleles segregate such that each gamete receives one allele.
• Occurs during Anaphase I of meiosis (disjunction and non-disjunction).
• Dominance: One allele will express as phenotype (dominant), the other remains silent (recessive).

Second Law: Law of Independent Assortment

• Inheritance of one gene is independent of another.
• Prophase I of meiosis is when this occurs (tetrad formation, crossing over, recombination).
• Genes may cross over or separate.
• Increases genetic diversity.

Biological Processes

• Meiosis:
  • Prophase I: Recombination, explains the second law.
  • Anaphase I: Segregation, explains the first law.

Additional Resources

• Encouragement to watch related videos on meiosis and genetics.
• Mention of renal physiology and surgery high yields courses available on the website.

Conclusion

• Recap of the importance of both laws in increasing genetic diversity and adaptability.
• Encouragement to subscribe, join, and visit the website for more resources.

• Website: medicosisperfectionitis.com
• Additional Courses: Renal Physiology, Surgery High Yields
• YouTube Channel: Subscribe, hit the bell, and join for more content.