🧬

Non-Mendelian Inheritance Patterns

Jul 7, 2025

Overview

This lecture explains non-Mendelian inheritance patterns, which do not follow classic Mendelian dominance, and covers incomplete dominance, codominance, polygenic traits, and epistasis.

Non-Mendelian Traits

  • Non-Mendelian traits do not follow the rule that a dominant allele always determines the phenotype.
  • Examples include snapdragons, human height, and speckled chickens.

Incomplete Dominance

  • Incomplete dominance occurs when neither allele is completely dominant, resulting in an intermediate phenotype.
  • Example: Crossing red (RR) and white (rr) snapdragons produces pink (Rr) offspring.
  • Crossing two pink (Rr) snapdragons yields red, pink, or white flowers.

Codominance

  • Codominance means both alleles are fully expressed in the phenotype.
  • Example: Crossing black (BB) and white (WW) chickens results in speckled (BW) offspring showing both colors.
  • Codominance uses different letter notation, and sometimes exponents, depending on classroom conventions.

Polygenic Traits

  • Polygenic traits are influenced by multiple genes, not just one gene pair.
  • Human height and skin color are polygenic; many gene pairs contribute to these traits.
  • Environmental factors like nutrition and sun exposure can affect the expression of polygenic traits but do not change the underlying genetics.

Epistasis

  • Epistasis occurs when one gene affects the expression of another gene.
  • Example: In llamas, a gene for wool pigment (B/b) is only expressed if another gene (C/c) is not homozygous recessive (cc).
  • If the llama's genotype is cc, no pigment is produced, resulting in albinism regardless of wool color genes.

Key Terms & Definitions

  • Non-Mendelian trait — a genetic trait that does not follow standard Mendelian inheritance.
  • Incomplete dominance — a pattern where heterozygotes display an intermediate phenotype.
  • Codominance — a pattern where both alleles in a gene pair are fully expressed.
  • Polygenic trait — a trait controlled by multiple genes.
  • Epistasis — when one gene’s expression depends on another gene.

Action Items / Next Steps

  • Watch videos on multiple alleles and sex-linked traits for further examples of non-Mendelian inheritance.