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Chapter 10: Ascending and Descending Pathways - Video -

Feb 24, 2025

Spinal Pathways Lecture Notes

Overview

  • Focus on spinal pathways, specifically the tracts that ascend and descend in the spinal cord.
  • Examines a transverse section of the spinal cord at level C8.

Spinal Cord Anatomy Recap

  • Grey Matter: H-shaped, central part of the spinal cord.
  • White Matter: Peripheral to grey matter, contains ascending and descending tracts.
  • Dorsal Horns: Located at the back.
  • Ventral Horns: Located anteriorly.
  • Central Canal: Located in the center.
  • Dorsal Median Sulcus: Located dorsally.
  • Ventral Median Fissure: Located ventrally.

Tracts and Fasciculi

  • Fasciculi: Bundles of axons, either ascending (sensory) or descending (motor).
  • Ascending tracts carry sensory information to the brain.
  • Descending tracts carry motor information from the brain to the periphery.

Ascending Tracts

  • Carry various sensory modalities:
    • Pain
    • Temperature
    • Tactile information (coarse to fine touch)
    • Vibration
    • Muscle and joint receptor information
  • Conscious vs. Subconscious Processing
    • Consciously processed information is sent to the cerebral cortex.
    • Subconsciously processed information, like proprioceptive data, goes to other brain areas such as the cerebellum.

Neuron Pathways

  • Three Neuron Sequence for consciously processed information:
    • First Order Neuron: Primary afferent, ipsilateral, cell bodies in the dorsal root ganglion.
      • Terminates by forming a synapse in the dorsal horn of grey matter or in the medulla oblongata.
    • Second Order Neuron: Crosses over (decussates) to the other side and ascends to the thalamus.
    • Third Order Neuron: Cell body in thalamus, projects to the somatosensory cortex, where sensation is perceived.

Important Terms

  • Ipsilateral: Same side.
  • Contralateral: Opposite side, used to describe the path after decussation.
  • Decussation: Crossing over of the second-order neuron to the opposite side.

Next Steps

  • Further examination of ascending and descending tracts within the spinal cord.