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Chapter 10: Ascending and Descending Pathways - Video -
Feb 24, 2025
Spinal Pathways Lecture Notes
Overview
Focus on spinal pathways, specifically the tracts that ascend and descend in the spinal cord.
Examines a transverse section of the spinal cord at level C8.
Spinal Cord Anatomy Recap
Grey Matter
: H-shaped, central part of the spinal cord.
White Matter
: Peripheral to grey matter, contains ascending and descending tracts.
Dorsal Horns
: Located at the back.
Ventral Horns
: Located anteriorly.
Central Canal
: Located in the center.
Dorsal Median Sulcus
: Located dorsally.
Ventral Median Fissure
: Located ventrally.
Tracts and Fasciculi
Fasciculi
: Bundles of axons, either ascending (sensory) or descending (motor).
Ascending tracts carry sensory information to the brain.
Descending tracts carry motor information from the brain to the periphery.
Ascending Tracts
Carry various sensory modalities:
Pain
Temperature
Tactile information (coarse to fine touch)
Vibration
Muscle and joint receptor information
Conscious vs. Subconscious Processing
Consciously processed information is sent to the cerebral cortex.
Subconsciously processed information, like proprioceptive data, goes to other brain areas such as the cerebellum.
Neuron Pathways
Three Neuron Sequence
for consciously processed information:
First Order Neuron
: Primary afferent, ipsilateral, cell bodies in the dorsal root ganglion.
Terminates by forming a synapse in the dorsal horn of grey matter or in the medulla oblongata.
Second Order Neuron
: Crosses over (decussates) to the other side and ascends to the thalamus.
Third Order Neuron
: Cell body in thalamus, projects to the somatosensory cortex, where sensation is perceived.
Important Terms
Ipsilateral
: Same side.
Contralateral
: Opposite side, used to describe the path after decussation.
Decussation
: Crossing over of the second-order neuron to the opposite side.
Next Steps
Further examination of ascending and descending tracts within the spinal cord.
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Full transcript