in this video lecture I will teach you leukemias that is a l l c ml AML and CLL with mnemonics and important points to remember these leukemias normally hematopoiesis Cascade hematopoetic stem cell gives rise to two type of cells that is myelite stem cell or myelite progenerator and lymphite stem cell are lymphide progenerator mylite progenerator gives rise to red blood cell myeloblast and platelets while myeloblast gave rise to neutrophils acinophils basophils and monoblast while lymphoblast gave rise to T cells and B cells and my light leukemia deer is uncontrolled production of cells of myelideline lineage while enlipide leukemia there is uncontrolled production of lymphide lineage leukemias for the purpose of Simplicity draw a straight line which shows spectrum of leukemia with respect to age if you remind from your innate me this Central is medial while the ends are lateral Central medial ends lateral leukemia with Double L are shown on lateral sites that is all or blastic leukemia on left side while cllr material leukemia on right side the medial contains leukemia with M that is CML and AML are shown on medial sides first trick is age for all age is around 10 years for CML age is 40 years for a mlh is 50 years while for CLL age is around 80 years if you don't have any idea about the given scenario of types of leukemia then you can decides on age of the patient second trick is Diagnostic lab findings in Al tdt are positive in a CML Philadelphia chromosomes which is translocation between chromosome 9 and 22 are presents in AML our rods and myeloparoxidase are presence in CLL there are smudge cells in CML C is for chromosomes Philadelphia which is translocation between 9 and 22 chromosomes M is for mesosplenomegaly and absence of lymphadenopathy is again very diagnostic feature of CML L is leukocytosis that is raised TLC on CBC in AML A is for our Rod which is aggregation of myeloparoxidase which form crystals m is myeloparoxidase which is cytoplasmic enzymes present in myeloblast of AML L is leukocytosis that is raised TLC on CBC and also for lymphadenopathy CLL clinical feature can be remembered with shell where s is for splenomegaly H is for hepatomegaly L is for lymphadenopathy and other L is for leukocytosis cln C represent crushed L little and L lymphocytes which is a very characteristic diagnostic laboratory finding of CLL called smudge cell Crush little lymphocytes called smudge cell guys if you like the content then please like the video subscribe the channel and share with friends