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Fundamentals of Human Physiology

Aug 23, 2024

Introduction to Human Physiology

Overview

  • Physiology is derived from Greek words:
    • Physis: Origin or nature
    • Logia: The study of
  • Focus on Human Physiology: Study of function and mechanisms of the human body.

Key Definitions

  • Physiology: Study of function and mechanisms in the body.
    • In contrast to Anatomy, which is the study of structure.
  • Regulation and Communication:
    • Fast communication via neurons.
    • Slow communication via the endocrine system.

Cellular Basics

  • Cell: Basic living unit of the body.
  • Approximately 100 trillion cells in the human body.

Internal Environment (Milieu Intérieur)

  • 60% of body weight is water:
    • Intracellular Fluid (ICF): Inside cells, 2/3 of total body water (~40 liters).
    • Extracellular Fluid (ECF): Outside cells, 1/3 of total body water (~20 liters).
  • ECF surrounds cells: Called the "internal environment."

Composition of ECF

  • Components:
    • Good stuff:
      • Ions: Sodium, Chloride, Bicarbonate
      • Nutrients: Amino acids, fatty acids, glucose
    • Bad stuff:
      • Waste Products: CO2 (excreted via lungs), other waste via kidneys

ECF Cycle

  • ECF circulates via blood:
    • From heart in arteries → Capillaries → Diffusion to tissues → Veins → Back to heart
  • ECF is present throughout the body.

Intracellular Fluid Components

  • Water and Ions:
    • Different ions compared to ECF:
      • Potassium, Magnesium, Phosphate are prevalent
      • Sodium and chloride more common in ECF
    • Ion flow is regulated, maintaining concentration differences.

Upcoming Topics

  • Homeostasis: To be discussed in the next video.
  • Not to be confused with Hemostasis.

Additional Information

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