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Comprehensive IGCSE Biology Study Notes
May 30, 2025
IGCSE Biology Video 91 Lecture Notes
Introduction
Lecture is an all-in-one guide for IGCSE Biology.
Aims to cover every specification point for confidence in exams.
Mention of available revision guides online.
Shared Features of Living Organisms
MRS. NERG
: Movement, Respiration, Sensitivity, Nutrition, Excretion, Reproduction, Growth.
Non-living things like viruses do not exhibit these functions.
Basic Cell Biology
Animal & Plant Cells Share:
Cell membranes, cytoplasm, nucleus, ribosomes, mitochondria.
Plant Cell Specific Organelles:
Cell wall, vacuole, chloroplasts.
Functions:
Nucleus: Control center of cell activities.
Cytoplasm: Site of chemical reactions.
Cell membrane: Regulates entry and exit of substances.
Ribosomes: Protein synthesis.
Cell wall (plant): Structure and protection.
Vacuole (plant): Maintains cell structure.
Chloroplasts (plant): Site of photosynthesis.
Eukaryotes vs. Prokaryotes
Eukaryotes:
Cells with membrane-bound organelles (e.g., animal cells, plants).
Prokaryotes:
Cells without membrane-bound organelles (e.g., bacteria, viruses).
Bacterial Cells:
Contain cell wall, sometimes slime capsule or flagella, no distinct nucleus, plasmids.
Pathogens
Pathogenic Bacteria:
Pneumococcus (pneumonia), Tuberculosis (TB).
Useful Bacteria:
Lactobacillus bulgaricus (yogurt production).
Viruses:
Non-living, always pathogenic (examples: flu virus, HIV).
Protists
Algae & Chlorella:
Plant-like with chloroplasts.
Amoeba:
Animal-like, no chloroplasts.
Plasmodium:
Pathogenic, causes malaria.
Fungi
Structure:
Similar to plant cells but no chloroplasts, cell wall made of chitin.
Nutrition:
Saprotrophic nutrition, secreting enzymes on dead matter.
Uses:
Yeast in beer and bread making, anaerobic respiration produces ethanol and CO2.
Classification and Storage
Five Kingdoms:
Plants, Animals, Protists, Bacteria, Fungi.
Carbohydrate Storage:
Glycogen in animals and fungi, starch in plants.
Organization in Organisms
Definitions: Cell, Tissue, Organ, Organ System, Organism.
Digestive System Example:
Organs - Stomach, esophagus, pancreas, intestines.
Reproduction and Growth
Zygote:
Formed from fertilization between sperm and egg.
Enzymes:
Biological catalysts with active sites.
Enzymes in Digestion
Amylase:
Breaks down starch to glucose.
Protease:
Breaks down proteins to amino acids.
Lipase:
Breaks down lipids to fatty acids and glycerol.
Enzyme Activity
Factors:
Temperature, pH.
Denaturation:
Enzymes lose function beyond optimal conditions.
Transport Mechanisms
Diffusion, Osmosis, Active Transport.
Amoeba:
Uses diffusion due to large surface area to volume ratio.
Photosynthesis and Leaves
Photosynthesis Equation:
Carbon dioxide + Water → Glucose + Oxygen.
Limiting Factors:
Light, temperature, carbon dioxide.
Leaf Structure:
Adaptations for photosynthesis.
Plant and Human Nutrition
Mineral Ions:
Nitrates and magnesium absorbed by active transport.
Deficiency Symptoms:
Yellow leaves (lack of magnesium), stunted growth (lack of nitrates).
Human Digestion
Processes:
Mechanical and chemical digestion.
Enzymes:
In the mouth, stomach, and intestines.
Bile:
Emulsification and neutralization of stomach acid.
Balanced Diet and Nutrients
Nutrients Needed:
Carbohydrates, proteins, fats, minerals, vitamins, water, fiber.
Vitamin and Mineral Deficiencies:
Scurvy (vitamin C), rickets (vitamin D), anemia (iron).
Respiration
Aerobic Respiration Equation:
Oxygen + Glucose → Carbon Dioxide + Water + Energy.
Anaerobic Respiration:
In muscles during strenuous exercise, produces lactic acid.
Circulatory System
Heart Structure:
Four chambers, double circulatory system.
Blood Flow:
Oxygenated and deoxygenated pathways.
Blood Components:
Red blood cells, white blood cells, plasma, platelets.
Lungs and Breathing
Breathing Process:
Inhalation and exhalation mechanics.
Alveoli:
Gas exchange surface area, thin walls for diffusion.
Excretion
In Plants:
Release of oxygen and carbon dioxide.
In Humans:
Sweat, urea, carbon dioxide.
Coordination and Response
Homeostasis:
Maintaining steady internal environment.
Human Nervous System:
Stimulus, receptor, response pathway.
Hormones:
Chemical messengers in the blood.
Reproduction
Sexual vs. Asexual Reproduction:
Genetic variation vs. genetic uniformity.
Human Reproductive Systems:
Structure and function of male and female systems.
Protein Synthesis
DNA and Genes:
Genotype, phenotype, alleles.
Punnett Squares:
Predicting offspring traits.
Genetic Engineering
Applications:
Production of insulin, GM plants.
Processes:
Use of plasmids as vectors, restriction and ligase enzymes.
Ecology
Community and Ecosystem Definitions:
Components and interactions.
Food Chains and Webs:
Energy flow, trophic levels, pyramids of numbers and biomass.
Human Impact on the Environment
Eutrophication:
Effects of fertilizers and sewage.
Greenhouse Effect:
Global warming causes and effects.
Acid Rain and Pollution:
Sources and environmental impacts.
Biological Resources Management
Agricultural Practices:
Greenhouses, fertilizers, pesticides.
Fermenters:
Use in microbial growth and production.
Selective Breeding:
Methods and benefits in agriculture.
Conclusion
Encouragement to use revision guides for further study.
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