Comprehensive IGCSE Biology Study Notes

May 30, 2025

IGCSE Biology Video 91 Lecture Notes

Introduction

  • Lecture is an all-in-one guide for IGCSE Biology.
  • Aims to cover every specification point for confidence in exams.
  • Mention of available revision guides online.

Shared Features of Living Organisms

  • MRS. NERG: Movement, Respiration, Sensitivity, Nutrition, Excretion, Reproduction, Growth.
  • Non-living things like viruses do not exhibit these functions.

Basic Cell Biology

  • Animal & Plant Cells Share: Cell membranes, cytoplasm, nucleus, ribosomes, mitochondria.
  • Plant Cell Specific Organelles: Cell wall, vacuole, chloroplasts.
  • Functions:
    • Nucleus: Control center of cell activities.
    • Cytoplasm: Site of chemical reactions.
    • Cell membrane: Regulates entry and exit of substances.
    • Ribosomes: Protein synthesis.
    • Cell wall (plant): Structure and protection.
    • Vacuole (plant): Maintains cell structure.
    • Chloroplasts (plant): Site of photosynthesis.

Eukaryotes vs. Prokaryotes

  • Eukaryotes: Cells with membrane-bound organelles (e.g., animal cells, plants).
  • Prokaryotes: Cells without membrane-bound organelles (e.g., bacteria, viruses).
  • Bacterial Cells: Contain cell wall, sometimes slime capsule or flagella, no distinct nucleus, plasmids.

Pathogens

  • Pathogenic Bacteria: Pneumococcus (pneumonia), Tuberculosis (TB).
  • Useful Bacteria: Lactobacillus bulgaricus (yogurt production).
  • Viruses: Non-living, always pathogenic (examples: flu virus, HIV).

Protists

  • Algae & Chlorella: Plant-like with chloroplasts.
  • Amoeba: Animal-like, no chloroplasts.
  • Plasmodium: Pathogenic, causes malaria.

Fungi

  • Structure: Similar to plant cells but no chloroplasts, cell wall made of chitin.
  • Nutrition: Saprotrophic nutrition, secreting enzymes on dead matter.
  • Uses: Yeast in beer and bread making, anaerobic respiration produces ethanol and CO2.

Classification and Storage

  • Five Kingdoms: Plants, Animals, Protists, Bacteria, Fungi.
  • Carbohydrate Storage: Glycogen in animals and fungi, starch in plants.

Organization in Organisms

  • Definitions: Cell, Tissue, Organ, Organ System, Organism.
  • Digestive System Example: Organs - Stomach, esophagus, pancreas, intestines.

Reproduction and Growth

  • Zygote: Formed from fertilization between sperm and egg.
  • Enzymes: Biological catalysts with active sites.

Enzymes in Digestion

  • Amylase: Breaks down starch to glucose.
  • Protease: Breaks down proteins to amino acids.
  • Lipase: Breaks down lipids to fatty acids and glycerol.

Enzyme Activity

  • Factors: Temperature, pH.
  • Denaturation: Enzymes lose function beyond optimal conditions.

Transport Mechanisms

  • Diffusion, Osmosis, Active Transport.
  • Amoeba: Uses diffusion due to large surface area to volume ratio.

Photosynthesis and Leaves

  • Photosynthesis Equation: Carbon dioxide + Water → Glucose + Oxygen.
  • Limiting Factors: Light, temperature, carbon dioxide.
  • Leaf Structure: Adaptations for photosynthesis.

Plant and Human Nutrition

  • Mineral Ions: Nitrates and magnesium absorbed by active transport.
  • Deficiency Symptoms: Yellow leaves (lack of magnesium), stunted growth (lack of nitrates).

Human Digestion

  • Processes: Mechanical and chemical digestion.
  • Enzymes: In the mouth, stomach, and intestines.
  • Bile: Emulsification and neutralization of stomach acid.

Balanced Diet and Nutrients

  • Nutrients Needed: Carbohydrates, proteins, fats, minerals, vitamins, water, fiber.
  • Vitamin and Mineral Deficiencies: Scurvy (vitamin C), rickets (vitamin D), anemia (iron).

Respiration

  • Aerobic Respiration Equation: Oxygen + Glucose → Carbon Dioxide + Water + Energy.
  • Anaerobic Respiration: In muscles during strenuous exercise, produces lactic acid.

Circulatory System

  • Heart Structure: Four chambers, double circulatory system.
  • Blood Flow: Oxygenated and deoxygenated pathways.
  • Blood Components: Red blood cells, white blood cells, plasma, platelets.

Lungs and Breathing

  • Breathing Process: Inhalation and exhalation mechanics.
  • Alveoli: Gas exchange surface area, thin walls for diffusion.

Excretion

  • In Plants: Release of oxygen and carbon dioxide.
  • In Humans: Sweat, urea, carbon dioxide.

Coordination and Response

  • Homeostasis: Maintaining steady internal environment.
  • Human Nervous System: Stimulus, receptor, response pathway.
  • Hormones: Chemical messengers in the blood.

Reproduction

  • Sexual vs. Asexual Reproduction: Genetic variation vs. genetic uniformity.
  • Human Reproductive Systems: Structure and function of male and female systems.

Protein Synthesis

  • DNA and Genes: Genotype, phenotype, alleles.
  • Punnett Squares: Predicting offspring traits.

Genetic Engineering

  • Applications: Production of insulin, GM plants.
  • Processes: Use of plasmids as vectors, restriction and ligase enzymes.

Ecology

  • Community and Ecosystem Definitions: Components and interactions.
  • Food Chains and Webs: Energy flow, trophic levels, pyramids of numbers and biomass.

Human Impact on the Environment

  • Eutrophication: Effects of fertilizers and sewage.
  • Greenhouse Effect: Global warming causes and effects.
  • Acid Rain and Pollution: Sources and environmental impacts.

Biological Resources Management

  • Agricultural Practices: Greenhouses, fertilizers, pesticides.
  • Fermenters: Use in microbial growth and production.
  • Selective Breeding: Methods and benefits in agriculture.

Conclusion

  • Encouragement to use revision guides for further study.