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Genetic Inheritance and Mendel's Findings

Mar 20, 2025

Genetic Inheritance & Genetic Crossing: DP IB Biology Revision Notes 2023

Inheritance: Gametes & Fertilisation

  • Gametes: Sex cells of an organism (e.g., sperm and egg in humans)
    • Egg is larger due to food reserves for embryo nourishment
    • Sperm has many mitochondria for movement energy
  • Fertilisation: Fusion of gametes to form a zygote
    • Gametes are formed during meiosis and are haploid (one copy of each chromosome)
    • Human gametes contain 23 single chromosomes
    • After fusion: zygote is diploid (two alleles of each gene)
    • Homozygous: Same alleles; Heterozygous: Different alleles

Genetic Crosses in Flowering Plants

  • Gregor Mendel: Conducted breeding experiments in pea plants
    • Known as the Father of Genetics
    • Experimented on characteristics like plant height and flower color
    • Transferred pollen manually to control fertilisation
    • Discovered predictable inheritance patterns
  • Mendel's Results:
    • First generation: Offspring show characteristic of one parent
    • Second generation: 3:1 ratio, characteristics of both parents
    • Identified concepts of dominant and recessive genes
    • Introduced the idea of alleles (different forms of a gene)

Monohybrid Crosses

  • Monohybrid Trait: Controlled by one gene
    • Typically involves two alleles (dominant or recessive, or co-dominant)
  • Punnett Grid: Predicts offspring's genotype and phenotype
    • Steps to construct a Punnett grid:
      1. Write parental phenotypes and genotypes
      2. Determine possible gamete genotypes
      3. Place parental genotypes on a grid
      4. Combine gametes to form offspring genotypes
      5. List phenotype and genotype ratios

Worked Example: Sweet Peas

  • Green (G) vs Yellow (g) Pods:
    • Step 1: Parental genotypes GG and gg
    • Step 2: Possible gametes G, g
    • Step 3: Setup Punnett grid
    • Step 4: Combine gametes (all offspring Gg, green)
    • Step 5: Cross F1 generation (Gg x Gg)
    • Step 6: Results in F2 generation (3:1 phenotype ratio, 1 GG: 2 Gg: 1 gg)

Plant Reproduction Methods

  • Self-Pollination: Male & female parts in the same flower/plant
  • Cross-Pollination: Between different plants by artificial means
    • Allows selection of desirable traits for breeding
    • Genetic crosses help predict breeding outcomes

The information extracted provides a framework for understanding genetic inheritance and the principles of genetic crossing in a biological context, specifically through the study of Mendel's experiments with pea plants.