Blood Circulation Pathways

Jul 11, 2025

Overview

This lecture explains the pathway of blood through the heart and circulatory system, focusing on the pulmonary and systemic circuits and how specific tissues receive oxygenated blood.

Heart Structure & Blood Flow

  • The heart has four chambers: right atrium, right ventricle, left atrium, and left ventricle.
  • Blood enters the right atrium, flows to the right ventricle, and is pumped to the lungs.
  • Oxygenated blood returns to the left atrium, moves to the left ventricle, and is pumped to the body.

Pulmonary Circulation

  • Starts at the right ventricle and sends deoxygenated blood to the lungs via the pulmonary trunk and arteries.
  • Pulmonary arteries carry blood away from the heart to the lungs.
  • Blood becomes oxygenated in lung capillaries and returns to the left atrium via pulmonary veins.
  • There are usually several pulmonary veins from each lung.

Systemic Circulation

  • Begins in the left ventricle and sends oxygenated blood through the aorta to the rest of the body.
  • Blood delivers oxygen to organs and tissues like the brain, liver, bones, and muscles.
  • Deoxygenated blood returns to the right atrium via the superior and inferior vena cava.

Oxygen Supply to Specific Tissues

  • Red blood cells (RBCs) do not use oxygen they transport because they lack mitochondria and nuclei.
  • The heart receives oxygenated blood from the coronary arteries, which branch off the aorta.
  • Coronary veins return deoxygenated blood directly to the right atrium, not the vena cava.

Oxygenation of the Lungs Themselves

  • The lungs receive oxygenated blood via bronchial arteries from systemic circulation.
  • Bronchial veins return blood to systemic veins, but most blood in lungs mixes at capillaries with pulmonary circulation.
  • Mixed blood from the lungs mostly returns via pulmonary veins to the heart.

Key Terms & Definitions

  • Pulmonary Circulation — Blood flow from the heart to lungs and back.
  • Systemic Circulation — Blood flow from the heart to the body and back.
  • Pulmonary Arteries — Vessels carrying deoxygenated blood from heart to lungs.
  • Pulmonary Veins — Vessels carrying oxygenated blood from lungs to heart.
  • Aorta — Largest artery distributing blood from left ventricle to body.
  • Vena Cava — Large veins returning deoxygenated blood to right atrium.
  • Coronary Vessels — Arteries and veins supplying blood to the heart muscle.
  • Bronchial Vessels — Arteries and veins supplying lung tissue itself.
  • Red Blood Cell (RBC) — Cell specialized for oxygen transport, without mitochondria or nucleus.

Action Items / Next Steps

  • Review the pathways and functions of pulmonary and systemic circulation.
  • Study diagrams of heart structure and blood vessel routes.
  • Prepare questions about mixed circulation in the lungs for the next lecture.