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Chemical Formula Mass Calculation

Jul 15, 2025

Overview

This lecture explains how to calculate the formula mass for covalent and ionic compounds by summing the average atomic masses of the atoms in their formulas.

Formula Mass Basics

  • Formula mass is determined by adding the average atomic masses of all atoms in a chemical formula.
  • For covalent compounds, the formula mass is the molecular mass and represents a single molecule.
  • For ionic compounds, the formula mass represents the sum for the formula unit, not a discrete molecule.

Calculating Molecular Mass for Covalent Compounds

  • The molecular mass of chloroform (CHCl₃) is 119.37 amu, calculated by adding masses for 1C, 1H, and 3Cl atoms.
  • For aspirin (C₉H₈O₄), the molecular mass is 180.15 amu, summing up 9C, 8H, and 4O atoms.
  • Example: Ibuprofen (C₁₃H₁₈O₂) has a molecular mass of 206.27 amu.
  • Practice: Acetaminophen (C₈H₉NO₂) has a molecular mass of 151.16 amu.

Calculating Formula Mass for Ionic Compounds

  • The formula mass of sodium chloride (NaCl) is 58.44 amu, computed as 1Na + 1Cl.
  • Use the average masses of neutral atoms when calculating ionic compound formula masses; electron differences are negligible.
  • Example: Aluminum sulfate [Al₂(SO₄)₃] has a formula mass of 342.14 amu (2Al, 3S, 12O).
  • Practice: Calcium phosphate [Ca₃(PO₄)₂] has a formula mass of 310.18 amu.

Key Terms & Definitions

  • Formula Mass — The sum of average atomic masses of all atoms in a compound’s formula.
  • Molecular Mass — Formula mass for a covalent molecule; represents a single molecule’s mass.
  • Ionic Compound — Substance comprised of positive and negative ions in specific ratios.
  • Atomic Mass Unit (amu) — Standard unit for expressing atomic and molecular masses.

Action Items / Next Steps

  • Practice calculating formula and molecular masses using various chemical formulas.
  • Review and memorize average atomic masses for common elements.
  • Complete any assigned textbook problems on formula mass calculations.